Title : Effect of low dose of berberine on the radioresistance of cervical cancer cells via a PI3K/HIF-1 pathway under nutrient-deprived conditions.

Pub. Date : 2020 Aug

PMID : 32412317






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1 Moreover, we found that most of the differentially expressed genes which were related to CDKN1B were the downstream molecules regulated by HIF-1alpha.Conclusion: The results indicated that berberine could dramatically overcome the low glucose and hypoxia induced radioresistance. Glucose hypoxia inducible factor 1 subunit alpha Homo sapiens