Iron

homeostatic iron regulator ; Mus musculus







164 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 22960056 Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload. 2013 Jan 4
52 23169885 Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells. 2013 Jan 7 2
53 23223430 An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia. 2013 Feb 14 2
54 23429074 A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice. 2013 Jun 1
55 23524968 Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice. 2013 Apr 2
56 23592271 Computerized image analysis of iron-stained macrophages. 2013 Sep 1
57 23705020 Absorption of manganese and iron in a mouse model of hemochromatosis. 2013 5
58 23874600 Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells. 2013 1
59 23922777 A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice. 2013 1
60 24155934 In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact. 2013 2
61 21943374 Iron-mediated retinal degeneration in haemojuvelin-knockout mice. 2012 Jan 15 2
62 22244935 Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6. 2012 Mar 15 1
63 22370144 Brain transcriptome perturbations in the Hfe(-/-) mouse model of genetic iron loading. 2012 Apr 11 2
64 22383097 Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice. 2012 Aug 4
65 22465035 Quantitative magnetic analysis reveals ferritin-like iron as the most predominant iron-containing species in the murine Hfe-haemochromatosis. 2012 Jul 3
66 22531912 Loss of central and peripheral CD8+ T-cell tolerance to HFE in mouse models of human familial hemochromatosis. 2012 Apr 1
67 22580926 Genetic modification of iron metabolism in mice affects the gut microbiota. 2012 Oct 1
68 22745741 Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation. 2012 1
69 22858058 Hepatic iron deposition does not predict extrahepatic iron loading in mouse models of hereditary hemochromatosis. 2012 Oct 1
70 20976594 Bone status in a mouse model of genetic hemochromatosis. 2011 Aug 2
71 21059897 Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis. 2011 Jan 27 11
72 21292994 Iron loading and oxidative stress in the Atm-/- mouse liver. 2011 Apr 1
73 21355094 Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice. 2011 Apr 28 3
74 21364282 The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. 2011 Apr 1
75 21427356 β2-microglobulin induces epithelial to mesenchymal transition and confers cancer lethality and bone metastasis in human cancer cells. 2011 Apr 1 1
76 21480335 Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. 2011 Apr 6
77 21745449 Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. 2011 Nov 3
78 21817060 Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis. 2011 Nov 4
79 20110460 Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies. 2010 Apr 2
80 20177050 Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice. 2010 Apr 22 4
81 20338170 Hepcidin expression does not rescue the iron-poor phenotype of Kupffer cells in Hfe-null mice after liver transplantation. 2010 Jul 11
82 20456487 Hepcidin treatment in Hfe-/- mice diminishes plasma iron without affecting erythropoiesis. 2010 Jun 1
83 20542038 Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. 2010 Aug 4
84 20712796 Hepcidin and Hfe in iron overload in beta-thalassemia. 2010 Aug 3
85 19191760 Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. 2009 May 1 3
86 19348938 Iron speciation study in Hfe knockout mice tissues: magnetic and ultrastructural characterisation. 2009 Jun 1
87 19591830 Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis. 2009 Oct 1
88 19700664 Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. 2009 Oct 22 1
89 19787063 Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum. 2009 Sep 29 1
90 19809161 Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. 2009 Nov 1
91 19824072 Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload. 2009 Dec 2
92 17719830 Bone marrow transplantation into hemochromatotic mice decreases hepatic and duodenal iron overload. 2008 3
93 18249176 Hfe acts in hepatocytes to prevent hemochromatosis. 2008 Feb 1
94 18316026 The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. 2008 Mar 2
95 18317567 Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis. 2008 Mar-Apr 1
96 18393371 The role of Hfe in transferrin-bound iron uptake by hepatocytes. 2008 May 7
97 18684963 Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. 2008 Aug 15 1
98 18694968 Increased susceptibility to Mycobacterium avium in hemochromatosis protein HFE-deficient mice. 2008 Oct 3
99 17207112 Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations. 2007 Jan 2
100 17255318 Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha. 2007 Feb 1