Pub. Date : 2013
PMID : 23705020
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hereditary hemochromatosis, an iron overload disease associated with excessive intestinal iron absorption, is commonly caused by loss of HFE gene function. | Iron | homeostatic iron regulator | Mus musculus |
2 | Hereditary hemochromatosis, an iron overload disease associated with excessive intestinal iron absorption, is commonly caused by loss of HFE gene function. | Iron | homeostatic iron regulator | Mus musculus |
3 | Loss of HFE function is known to alter the intestinal expression of DMT1 (divalent metal transporter-1) and Fpn (ferroportin), transporters that have been implicated in absorption of both iron and manganese. | Iron | homeostatic iron regulator | Mus musculus |
4 | Intestinal absorption of (59)Fe was increased and clearance of injected (59)Fe was also increased in Hfe(-/-) mice compared to controls. | Iron | homeostatic iron regulator | Mus musculus |
5 | Intestinal absorption of (59)Fe was increased and clearance of injected (59)Fe was also increased in Hfe(-/-) mice compared to controls. | Iron | homeostatic iron regulator | Mus musculus |