Title : Absorption of manganese and iron in a mouse model of hemochromatosis.

Pub. Date : 2013

PMID : 23705020






5 Functional Relationships(s)
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Protein Name
Organism
1 Hereditary hemochromatosis, an iron overload disease associated with excessive intestinal iron absorption, is commonly caused by loss of HFE gene function. Iron homeostatic iron regulator Mus musculus
2 Hereditary hemochromatosis, an iron overload disease associated with excessive intestinal iron absorption, is commonly caused by loss of HFE gene function. Iron homeostatic iron regulator Mus musculus
3 Loss of HFE function is known to alter the intestinal expression of DMT1 (divalent metal transporter-1) and Fpn (ferroportin), transporters that have been implicated in absorption of both iron and manganese. Iron homeostatic iron regulator Mus musculus
4 Intestinal absorption of (59)Fe was increased and clearance of injected (59)Fe was also increased in Hfe(-/-) mice compared to controls. Iron homeostatic iron regulator Mus musculus
5 Intestinal absorption of (59)Fe was increased and clearance of injected (59)Fe was also increased in Hfe(-/-) mice compared to controls. Iron homeostatic iron regulator Mus musculus