Title : Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.

Pub. Date : 2013 Jan 7

PMID : 23169885






2 Functional Relationships(s)
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Protein Name
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1 PURPOSE: Hemochromatosis is a disorder of iron overload arising mostly from mutations in HFE. Iron homeostatic iron regulator Mus musculus
2 HFE is expressed in retinal pigment epithelium (RPE), and Hfe(-/-) mice develop age-related iron accumulation and retinal degeneration associated with RPE hyperproliferation. Iron homeostatic iron regulator Mus musculus