Guanine Nucleotides

vav guanine nucleotide exchange factor 1 ; Homo sapiens







55 Article(s)
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1 34252536 Regulatory interplay between Vav1, Syk and β-catenin occurs in lung cancer cells. 2021 Oct 1
2 35237130 Vav3-Deficient Astrocytes Enhance the Dendritic Development of Hippocampal Neurons in an Indirect Co-culture System. 2021 1
3 31548614 Genome-wide screening identifies novel genes implicated in cellular sensitivity to BRAFV600E expression. 2020 Jan 1
4 31974114 Vav2 lacks Ca2+ entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42. 2020 Mar 13 1
5 28255536 Central role of PI3K-SYK interaction in fibrinogen-induced lamellipodia and filopodia formation in platelets. 2016 Dec 1
6 24501217 Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells. 2014 Apr 3 1
7 22203994 Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. 2012 Jan 10 1
8 22432082 Vav1 in hematologic neoplasms, a mini review. 2012 1
9 22467863 Radixin regulates cell migration and cell-cell adhesion through Rac1. 2012 Jul 15 1
10 22692505 Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival. 2012 Jul 26 1
11 21151158 The distinct role of guanine nucleotide exchange factor Vav1 in Bcl-2 transcription and apoptosis inhibition in Jurkat leukemia T cells. 2011 Jan 1
12 21606197 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. 2011 Jul 1
13 22043008 PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase. 2011 Dec 1 1
14 20140013 VAV2 regulates epidermal growth factor receptor endocytosis and degradation. 2010 Apr 29 1
15 19088377 Rac GTPases play critical roles in early T-cell development. 2009 Apr 23 1
16 19435813 Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo. 2009 May 1
17 19672294 Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity. 2009 Aug 12 2
18 19933863 Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. 2009 Dec 15 1
19 18589439 Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. 2008 Jul 25 3
20 18925966 The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer. 2008 Oct 16 1
21 17060455 The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. 2007 Jan 1
22 17275330 Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex. 2007 May 1
23 17339487 The Src family kinases Hck and Fgr regulate neutrophil responses to N-formyl-methionyl-leucyl-phenylalanine. 2007 Mar 15 1
24 17550897 The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes. 2007 Aug 10 1
25 16397238 Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion. 2006 Jan 1 1
26 16684890 Altered proximal T cell receptor (TCR) signaling in human CD4+CD25+ regulatory T cells. 2006 Jul 1
27 15618286 Novel association of Vav2 and Nek3 modulates signaling through the human prolactin receptor. 2005 Apr 1
28 15661896 Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. 2005 Feb 1 1
29 16213217 The Rho/Rac-family guanine nucleotide exchange factor VAV-1 regulates rhythmic behaviors in C. elegans. 2005 Oct 7 1
30 14607270 Vav proteins, masters of the world of cytoskeleton organization. 2004 Jan 1
31 14709332 Association of PI 3-K with tyrosine phosphorylated Vav is essential for its activity in neutrophil-like maturation of myeloid cells. 2004 Apr 1
32 14764585 Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. 2004 Apr 30 1
33 15249579 Vav GEFs are required for beta2 integrin-dependent functions of neutrophils. 2004 Jul 19 1
34 15456756 Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. 2004 Dec 24 1
35 12616499 Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse. 2003 Mar 1
36 11716957 In vitro, Vav is a regulated guanine nucleotide dissociation inhibitor for Ras. 2002 Jan 1 1
37 11813163 Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1. 2002 Feb 1
38 11859076 Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway. 2002 May 3 1
39 12177050 Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity. 2002 Oct 18 1
40 12386169 Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways. 2002 Dec 20 2
41 11262396 Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte. 2001 Jun 15 1
42 11470914 Rac1 mediates STAT3 activation by autocrine IL-6. 2001 Jul 31 1
43 10713454 Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors. 2000 Mar 7 1
44 10748082 Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. 2000 May 19 1
45 10760587 Genomic organization and regulation of the vav proto-oncogene. 2000 Apr 25 1
46 10938113 Vav family proteins couple to diverse cell surface receptors. 2000 Sep 1
47 10022833 Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. 1999 Feb 15 1
48 9209406 The signal transduction through Grb2/Ash in hematopoietic cells. 1997 Apr 1
49 8677749 Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells. 1996 2
50 8724692 Vav: function and regulation in hematopoietic cell signaling. 1996 May 1