Title : Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways.

Pub. Date : 2002 Dec 20

PMID : 12386169






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 One well studied regulator of Rho GTPases is Vav1; a hematopoietic cell-specific guanine nucleotide exchange factor critical for signaling in T cells, including stimulation of the nuclear factor of activated T cells (NFAT). Guanine Nucleotides vav guanine nucleotide exchange factor 1 Homo sapiens
2 Surprisingly, Vav1 associates with Ly-GDI, a hematopoietic cell-specific guanine nucleotide dissociation inhibitor of Rac. Guanine Nucleotides vav guanine nucleotide exchange factor 1 Homo sapiens