Cysteine

immunglobulin heavy chain variable region ; Homo sapiens







45 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32569010 Toward the Clinical Development and Validation of a Thy1-Targeted Ultrasound Contrast Agent for the Early Detection of Pancreatic Ductal Adenocarcinoma. 2020 Nov 1
2 31332748 Engineering Antibodies with C-Terminal Sortase-Mediated Modification for Targeted Nanomedicine. 2019 1
3 31535232 Construction and characterization of immunoliposomes targeting fibroblast growth factor receptor 3. 2019 Sep 18 4
4 31733318 Simple strategy for single-chain fragment antibody-conjugated probe construction. 2019 Dec 15 1
5 28643153 A 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic Colorectal Cancer Model. 2018 Feb 8
6 29553717 Impact of Site-Specific Conjugation of ScFv to Multifunctional Nanomedicines Using Second Generation Maleimide. 2018 May 16 2
7 29662239 Elimination of TDP-43 inclusions linked to amyotrophic lateral sclerosis by a misfolding-specific intrabody with dual proteolytic signals. 2018 Apr 16 1
8 29737435 Anti-EpCAM scFv gadolinium chelate: a novel targeted MRI contrast agent for imaging of colorectal cancer. 2018 Oct 1
9 30130449 Characterization and analysis of scFv-IgG bispecific antibody size variants. 2018 Nov-Dec 3
10 30352511 Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro. 2018 Nov 21 1
11 30405887 Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging. 2018 Oct 9 4
12 28126683 PET imaging of 64Cu-DOTA-scFv-anti-PSMA lipid nanoparticles (LNPs): Enhanced tumor targeting over anti-PSMA scFv or untargeted LNPs. 2017 Apr 2
13 28755586 An unusual cysteine VL87 affects the antibody fragment conformations without interfering with the disulfide bond formation. 2017 Oct 1
14 29067565 Simple, mild, one-step labelling of proteins with gallium-68 using a tris(hydroxypyridinone) bifunctional chelator: a 68Ga-THP-scFv targeting the prostate-specific membrane antigen. 2017 Oct 25 2
15 24262918 The influence of antibody fragment format on phage display based affinity maturation of IgG. 2014 Jan-Feb 1
16 32481827 Dependence of nanoparticle-cell recognition efficiency on the surface orientation of scFv targeting ligands. 2013 Jul 4 2
17 22484084 A novel disulfide-stabilized single-chain variable antibody fragment against rabies virus G protein with enhanced in vivo neutralizing potency. 2012 Jun 2
18 19327975 Single chain fragment variable recombinant antibody functionalized gold nanoparticles for a highly sensitive colorimetric immunoassay. 2009 May 15 4
19 18290668 Engineering peptide linkers for scFv immunosensors. 2008 Mar 15 1
20 18790696 Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice. 2008 Nov 30 2
21 17613658 Single-chain Fv immunoliposomes for the targeting of fibroblast activation protein-expressing tumor stromal cells. 2007 Jul 1
22 17944370 [Recombinant design and expression of human anti-rabies virus ScdsFv]. 2007 Aug 1
23 16427706 Oriented immobilisation of engineered single-chain antibodies to develop biosensors for virus detection. 2006 Jun 5
24 16492049 Rigid, specific, and discrete gold nanoparticle/antibody conjugates. 2006 Mar 1 1
25 16760193 Development of tumor targeting anti-MUC-1 multimer: effects of di-scFv unpaired cysteine location on PEGylation and tumor binding. 2006 Aug 2
26 16868004 A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration. 2006 Oct 1
27 16898953 Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura. 2006 Nov 1
28 15656582 Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals. 2005 Jan-Feb 1
29 15679346 Single-chain fragment variable antibody piezoimmunosensors. 2005 Feb 1 8
30 16192357 A label-free immunosensor array using single-chain antibody fragments. 2005 Oct 11 1
31 15157618 Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105). 2004 May 27 1
32 12121127 Quantitation of the tumor-targeting properties of antibody fragments conjugated to cell-permeating HIV-1 TAT peptides. 2002 Jul-Aug 2
33 12489850 Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes. 2002 Mar 1
34 11162401 Production of functionalized single-chain Fv antibody fragments binding to the ED-B domain of the B-isoform of fibronectin in Pichia pastoris. 2001 Feb 2
35 11320404 Single chain Fv: a ligand in receptor-mediated gene delivery. 2001 Apr 3
36 9551966 Harnessing Syk family tyrosine kinases as signaling domains for chimeric single chain of the variable domain receptors: optimal design for T cell activation. 1998 Jan 1 1
37 9636161 Antigen binding forces of individually addressed single-chain Fv antibody molecules. 1998 Jun 23 1
38 9637257 An intrinsically stable antibody scFv fragment can tolerate the loss of both disulfide bonds and fold correctly. 1998 May 15 2
39 9748318 Mutual stabilization of VL and VH in single-chain antibody fragments, investigated with mutants engineered for stability. 1998 Sep 22 1
40 9026037 Optimization of conditions for formation and analysis of anti-CD19 FVS191 single-chain Fv homodimer (scFv')2. 1997 Jan-Feb 2
41 9194170 Two amino acid mutations in an anti-human CD3 single chain Fv antibody fragment that affect the yield on bacterial secretion but not the affinity. 1997 Apr 2
42 8965166 Technetium-99m radiolabeling using a phage-derived single-chain Fv with a C-terminal cysteine. 1996 May 1
43 7628706 A single expression system for the display, purification and conjugation of single-chain antibodies. 1995 Jul 4 1
44 8575837 Characterization of an anti-CD44 single-chain FV antibody that stimulates natural killer cell activity and induces TNF alpha release. 1995 Nov 1
45 9636285 Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria. 1995 Oct 2