Title : Oriented immobilisation of engineered single-chain antibodies to develop biosensors for virus detection.

Pub. Date : 2006 Jun

PMID : 16427706






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Single chain variable fragment (scFv) molecules were selected from a synthetic phage display library then cloned into a generic vector for expression of the scFv fused to the light chain constant domain of human immunoglobulin with a C-terminal cysteine residue (scFvC(L)cys). Cysteine immunglobulin heavy chain variable region Homo sapiens
2 Single chain variable fragment (scFv) molecules were selected from a synthetic phage display library then cloned into a generic vector for expression of the scFv fused to the light chain constant domain of human immunoglobulin with a C-terminal cysteine residue (scFvC(L)cys). Cysteine immunglobulin heavy chain variable region Homo sapiens
3 Single chain variable fragment (scFv) molecules were selected from a synthetic phage display library then cloned into a generic vector for expression of the scFv fused to the light chain constant domain of human immunoglobulin with a C-terminal cysteine residue (scFvC(L)cys). Cysteine immunglobulin heavy chain variable region Homo sapiens
4 Single chain variable fragment (scFv) molecules were selected from a synthetic phage display library then cloned into a generic vector for expression of the scFv fused to the light chain constant domain of human immunoglobulin with a C-terminal cysteine residue (scFvC(L)cys). Cysteine immunglobulin heavy chain variable region Homo sapiens
5 ScFv molecules lacking the C-terminal cysteine performed poorly in similar experiments. Cysteine immunglobulin heavy chain variable region Homo sapiens