Fluorouracil

signal transducer and activator of transcription 3 ; Homo sapiens







29 Article(s)
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1 35157912 Schisandrin B suppresses gastric cancer cell growth and enhances the efficacy of chemotherapy drug 5-FU in vitro and in vivo. 2022 Apr 5 2
2 35483272 Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer. 2022 Jun 1
3 33599179 JAK2/STAT3 inhibitor reduced 5-FU resistance and autophagy through ATF6-mediated ER stress. 2021 Feb 18 5
4 33634982 Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF-kB signaling pathways synergistically. 2021 Feb 2
5 33727040 Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages. 2021 May 15 1
6 34226586 miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells. 2021 Jul 5 1
7 32581212 Enalapril overcomes chemoresistance and potentiates antitumor efficacy of 5-FU in colorectal cancer by suppressing proliferation, angiogenesis, and NF-κB/STAT3-regulated proteins. 2020 Jun 24 1
8 32904684 NHE1 Mediates 5-Fu Resistance in Gastric Cancer via STAT3 Signaling Pathway. 2020 3
9 33082817 Feng-Liao-Chang-Wei-Kang Combined with 5-Fluorouracil Synergistically Suppresses Colitis-Associated Colorectal Cancer via the IL-6/STAT3 Signalling Pathway. 2020 2
10 30548625 Bile salt (glycochenodeoxycholate acid) induces cell survival and chemoresistance in hepatocellular carcinoma. 2019 Jul 1
11 30993753 Identification of Nrf2/STAT3 axis in induction of apoptosis through sub-G 1 cell cycle arrest mechanism in HT-29 colon cancer cells. 2019 Aug 2
12 31324203 Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells. 2019 Jul 19 5
13 31582208 H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA. 2019 Nov 26 2
14 29777330 Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer. 2018 Jun 1
15 30250641 Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells. 2018 Aug 31 2
16 30468567 A Biodegradable Stent with Surface Functionalization of Combined-Therapy Drugs for Colorectal Cancer. 2018 Dec 2
17 28531805 Troxerutin (TXN) potentiated 5-Fluorouracil (5-Fu) treatment of human gastric cancer through suppressing STAT3/NF-κB and Bcl-2 signaling pathways. 2017 Aug 5
18 28591704 Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway. 2017 Jul 25 2
19 29113268 JAB1-STAT3 activation loop is associated with recurrence following 5-fluorouracil-based adjuvant chemotherapy in human colorectal cancer. 2017 Nov 5
20 25617735 Inhibition of STAT3/cyclinD1 pathway promotes chemotherapeutic sensitivity of colorectal caner. 2015 Feb 20 1
21 26492225 Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil. 2015 1
22 23934972 STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo. 2014 Feb 15 2
23 25063444 Interleukin 22 protects colorectal cancer cells from chemotherapy by activating the STAT3 pathway and inducing autocrine expression of interleukin 8. 2014 Oct 2
24 22205702 Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition. 2012 Feb 17 1
25 21651859 [The inhibitory effect of RNA interference on STAT3 expression in liver cancer cell line SMMC7721]. 2011 Jun 1
26 18205257 Effects of Wei Chang An on expression of multiple genes in human gastric cancer grafted onto nude mice. 2008 Feb 7 1
27 15682485 Activation of STAT3 signaling in human stomach adenocarcinoma drug-resistant cell line and its relationship with expression of vascular endothelial growth factor. 2005 Feb 14 2
28 15730734 [The impact of decreased Stat3 activation on 5-fluorouracil resistance of human gastric cancer cell line]. 2004 Dec 4
29 11927016 The roles of JNK1 and Stat3 in the response of head and neck cancer cell lines to combined treatment with all-trans-retinoic acid and 5-fluorouracil. 2002 Mar 3