Title : Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer.

Pub. Date : 2018 Jun

PMID : 29777330






1 Functional Relationships(s)
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1 Further mechanistic studies determined that BZA treatment enhanced 5-FU anti-tumor activation by inhibiting the IL-6/GP130 signaling pathway and the phosphorylation status of the downstream effectors AKT, ERK and STAT3. Fluorouracil signal transducer and activator of transcription 3 Homo sapiens