Title : Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells.

Pub. Date : 2018 Aug 31

PMID : 30250641






2 Functional Relationships(s)
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1 We herein showed that resveratrol and 5-FU combination treatments caused the anti-cancer activities by simultaneously inhibiting STAT3 and Akt signaling pathways. Fluorouracil signal transducer and activator of transcription 3 Homo sapiens
2 Resveratrol and 5-FU treatments inhibited STAT3 phosphorylation and its binding to the promoter region of human telomerase reverse transcriptase (hTERT). Fluorouracil signal transducer and activator of transcription 3 Homo sapiens