Pub. Date : 2004 Dec
PMID : 15730734
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [The impact of decreased Stat3 activation on 5-fluorouracil resistance of human gastric cancer cell line]. | Fluorouracil | signal transducer and activator of transcription 3 | Homo sapiens |
| 2 | OBJECTIVE: To investigate the relationship between different activation of Stat3 signaling and the drug resistance mechanisms in two human gastric cancer cell lines, 5-fluorouracil (5-FU) resistant cell line and its parental cell line. | Fluorouracil | signal transducer and activator of transcription 3 | Homo sapiens |
| 3 | OBJECTIVE: To investigate the relationship between different activation of Stat3 signaling and the drug resistance mechanisms in two human gastric cancer cell lines, 5-fluorouracil (5-FU) resistant cell line and its parental cell line. | Fluorouracil | signal transducer and activator of transcription 3 | Homo sapiens |
| 4 | CONCLUSIONS: The decreased Stat3 activation in 5-FU resistant human gastric cancer cell line SGC7901/R is related to the drug resistance mechanisms and may be correlated with the lower VEGF expression. | Fluorouracil | signal transducer and activator of transcription 3 | Homo sapiens |