Tyrosine

signal transducer and activator of transcription 3 ; Homo sapiens







754 Article(s)
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51 30872773 Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis. 2019 Mar 14 1
52 30910759 Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance. 2019 Sep 1
53 30981183 Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells. 2019 Jun 1
54 31058868 Novel Galiellalactone Analogues Can Target STAT3 Phosphorylation and Cause Apoptosis in Triple-Negative Breast Cancer. 2019 May 3 1
55 31068940 CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter. 2019 1
56 31080186 Fraxetin Suppresses Proliferation of Non-Small-Cell Lung Cancer Cells via Preventing Activation of Signal Transducer and Activator of Transcription 3. 2019 May 3
57 31170499 Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine. 2019 Sep 2
58 31277507 Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells. 2019 Jul 4 1
59 31321245 STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn's Disease. 2019 3
60 31323961 Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells. 2019 Jul 9 1
61 31346092 A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance. 2019 Aug 13 2
62 31409371 Novel interactions between ERα-36 and STAT3 mediate breast cancer cell migration. 2019 Aug 13 1
63 31427441 STAT3 Targets ERR-α to Promote Epithelial-Mesenchymal Transition, Migration, and Invasion in Triple-Negative Breast Cancer Cells. 2019 Nov 4
64 31462771 Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. 2019 Sep 1
65 31481496 Serine-Phosphorylated STAT3 Promotes Tumorigenesis via Modulation of RNA Polymerase Transcriptional Activity. 2019 Oct 15 1
66 31491838 Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor. 2019 Sep 5 2
67 31537377 Gp130 degradation induced by epirubicin contributes to chemotherapy efficacy. 2019 Nov 12 1
68 31557897 STAT3 and STAT5 Activation in Solid Cancers. 2019 Sep 25 2
69 31619200 STAT3 induces G9a to exacerbate HER3 expression for the survival of epidermal growth factor receptor-tyrosine kinase inhibitors in lung cancers. 2019 Oct 16 1
70 31684051 Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy. 2019 Nov 2 2
71 31752959 Pre-metastatic niche triggers SDF-1/CXCR4 axis and promotes organ colonisation by hepatocellular circulating tumour cells via downregulation of Prrx1. 2019 Nov 21 1
72 31861720 Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity. 2019 Dec 19 2
73 31878046 Attenuation of STAT3 Signaling Cascade by Daidzin Can Enhance the Apoptotic Potential of Bortezomib against Multiple Myeloma. 2019 Dec 23 1
74 28497593 Polymorphism of receptor-type tyrosine-protein phosphatase delta gene in the development of non-alcoholic fatty liver disease. 2018 Jan 3
75 28558479 Mechanisms of Mitochondrial Redox Signaling in Psychosocial Stress-Responsive Systems: New Insights into an Old Story. 2018 Mar 20 2
76 28881473 The classic signalling and trans-signalling of interleukin-6 are both injurious in podocyte under high glucose exposure. 2018 Jan 1
77 29207010 The potential inhibitory effects of miR‑19b on vulnerable plaque formation via the suppression of STAT3 transcriptional activity. 2018 Feb 2
78 29402895 Visualization and quantification of dynamic STAT3 homodimerization in living cells using homoFluoppi. 2018 Feb 5 2
79 29431732 STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. 2018 Mar 1 2
80 29456111 Methyllucidone inhibits STAT3 activity by regulating the expression of the protein tyrosine phosphatase MEG2 in DU145 prostate carcinoma cells. 2018 Mar 1 2
81 29488000 Bilateral activation of STAT3 by phosphorylation at the tyrosine-705 (Y705) and serine-727 (S727) positions and its nuclear translocation in primary sensory neurons following unilateral sciatic nerve injury. 2018 Jul 2
82 29555504 Alantolactone suppresses APOC3 expression and alters lipid homeostasis in L02 liver cells. 2018 Jun 5 1
83 29660364 Silibinin is a direct inhibitor of STAT3. 2018 Jun 1
84 29765448 Overexpressed HO-1 is associated with reduced STAT3 activation in preeclampsia placenta and inhibits STAT3 phosphorylation in placental JEG-3 cells under hypoxia. 2018 Apr 4
85 29774125 The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma. 2018 Apr 24 1
86 29807795 Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells. 2018 Aug 1 2
87 29857127 Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model. 2018 Sep 1 1
88 29861864 PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma. 2018 May 18 1
89 29873274 STAT3: a multifaceted oncoprotein. 2018 Apr 2
90 30043217 Bioassay-guided isolation of cantharidin from blister beetles and its anticancer activity through inhibition of epidermal growth factor receptor-mediated STAT3 and Akt pathways. 2018 Sep 1
91 30127519 The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway. 2018 Aug 20 1
92 30135654 Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3. 2018 2
93 30197757 Zac1 regulates IL-11 expression in osteoarthritis. 2018 Aug 21 1
94 30206377 Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. 2018 Sep 11 1
95 30208623 Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling. 2018 Sep 11 2
96 30251272 Sesquiterpene lactones-enriched fraction of Inula helenium L. induces apoptosis through inhibition of signal transducers and activators of transcription 3 signaling pathway in MDA-MB-231 breast cancer cells. 2018 Dec 1
97 30261753 Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1. 2018 Dec 2
98 30455079 Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes. 2018 Nov 1
99 26705936 Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals. 2017 Jan 2
100 27660268 Role of STAT3 in Genesis and Progression of Human Malignant Gliomas. 2017 Oct 1