Title : CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter.

Pub. Date : 2019

PMID : 31068940






1 Functional Relationships(s)
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1 In particular, we found that CD28-activated RelA/NF-kappaB induces the expression of IL-6 that, in a positive feedback loop, mediates the activation and nuclear translocation of tyrosine phosphorylated STAT3 (pSTAT3). Tyrosine signal transducer and activator of transcription 3 Homo sapiens