Title : Pharmacological inhibition of mTORC1 prevents over-activation of the primordial follicle pool in response to elevated PI3K signaling.

Pub. Date : 2013

PMID : 23326514






1 Functional Relationships(s)
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1 To study the functional and pathological roles of elevated mTORC1 signaling in the oocytes, we treated the Pten-mutant mice with the specific mTORC1 inhibitor rapamycin. Sirolimus phosphatase and tensin homolog Mus musculus