Pub. Date : 2021 Jan 11
PMID : 33186548
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Spindle assembly is spatially regulated by a chromosome-derived Ran- GTP gradient. | Guanosine Triphosphate | RAN, member RAS oncogene family | Homo sapiens |
| 2 | However, it is unclear whether the Ran-GTP gradient equivalently activates SAFs that localize at distinct spindle regions. | Guanosine Triphosphate | RAN, member RAS oncogene family | Homo sapiens |
| 3 | We demonstrated that Ran-GTP and importin-beta coordinately promote HURP"s dynamic microtubule binding-dissociation cycle, which maintains HURP near chromosomes during metaphase. | Guanosine Triphosphate | RAN, member RAS oncogene family | Homo sapiens |