| 1 |
35191521 | ATR inhibitor AZD6738 increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting repair of DNA damage. | 2022 Apr |
1 |
| 2 |
35245520 | Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway. | 2022 May 1 |
1 |
| 3 |
35326689 | In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network. | 2022 Mar 17 |
1 |
| 4 |
35416117 | Discoidin domain receptor 1a (DDR1a) confers 5-fluorouracil cytotoxicity in LoVo cell via PI3K/AKT/Bcl-2 pathway. | 2022 Apr |
1 |
| 5 |
35596172 | Mir-675-5p supports hypoxia-induced drug resistance in colorectal cancer cells. | 2022 May 20 |
1 |
| 6 |
30990333 | Inhibitory effects and molecular mechanisms of pentagalloyl glucose in combination with 5-FU on aggressive phenotypes of HepG2 cells. | 2021 Mar |
1 |
| 7 |
33030957 | Loss of tumor intrinsic PD-L1 confers resistance to drug-induced apoptosis in human colon cancer. | 2021 Jan |
2 |
| 8 |
33489855 | Celecoxib induces apoptosis through Akt inhibition in 5-fluorouracil-resistant gastric cancer cells. | 2021 Jan |
1 |
| 9 |
34185243 | The IL-6/STAT Signaling Pathway and PPARα Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity. | 2021 Jun 29 |
1 |
| 10 |
34627212 | Anti-apoptotic effect of Buchholzia coriacea Engl. stem back extracts on AsPC-1 and mechanisms of action. | 2021 Oct 9 |
1 |
| 11 |
31753399 | Synthesis and characterization of thiosemicarbazone-functionalized organoruthenium (II)-arene complexes: Investigation of antitumor characteristics in colorectal cancer cell lines. | 2020 Jan |
1 |
| 12 |
31969973 | Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways. | 2020 |
1 |
| 13 |
32509181 | Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway. | 2020 |
1 |
| 14 |
32665777 | Phenoxodiol sensitizes metastatic colorectal cancer cells to 5-fluorouracil- and oxaliplatin-induced apoptosis through intrinsic pathway. | 2020 |
2 |
| 15 |
32945504 | Ginsenoside Rg3 enhances the anticancer effect of 5‑FU in colon cancer cells via the PI3K/AKT pathway. | 2020 Oct |
1 |
| 16 |
32975155 | Apoptosis pathway in the combined treatment of x-ray and 5-FU-loaded triblock copolymer-coated magnetic nanoparticles. | 2020 Aug |
1 |
| 17 |
30741544 | (-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway. | 2019 Mar 6 |
1 |
| 18 |
30915129 | MiR-214 sensitizes human colon cancer cells to 5-FU by targeting Hsp27. | 2019 |
1 |
| 19 |
31072625 | miR-145 Regulates the sensitivity of esophageal squamous cell carcinoma cells to 5-FU via targeting REV3L. | 2019 Jul |
1 |
| 20 |
31352611 | 5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-xL. | 2019 Nov |
2 |
| 21 |
31372308 | Doublecotin-Like Kinase 1 Increases Chemoresistance of Colorectal Cancer Cells through the Anti-Apoptosis Pathway. | 2019 |
3 |
| 22 |
31623083 | Detection of Superoxide Alterations Induced by 5-Fluorouracil on HeLa Cells with a Cell-Based Biosensor. | 2019 Oct 16 |
1 |
| 23 |
29183726 | GSDME mediates caspase-3-dependent pyroptosis in gastric cancer. | 2018 Jan 1 |
1 |
| 24 |
29277783 | Up-regulation of UVRAG by HDAC1 Inhibition Attenuates 5FU-induced Cell Death in HCT116 Colorectal Cancer Cells. | 2018 Jan |
2 |
| 25 |
29601890 | The silencing of replication protein A1 induced cell apoptosis via regulating Caspase 3. | 2018 May 15 |
1 |
| 26 |
29695684 | Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480. | 2018 Apr 26 |
1 |
| 27 |
29719602 | Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer. | 2018 Apr 6 |
1 |
| 28 |
29795190 | Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity. | 2018 May 23 |
1 |
| 29 |
29914576 | Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents. | 2018 Jun 19 |
1 |
| 30 |
29921390 | Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells. | 2018 May-Jun |
1 |
| 31 |
30328537 | Autophagy Inhibitor (LY294002) and 5-fluorouracil (5-FU) Combination-Based Nanoliposome for Enhanced Efficacy Against Esophageal Squamous Cell Carcinoma. | 2018 Oct 17 |
1 |
| 32 |
31949673 | Knockdown of PHGDH potentiates 5-FU cytotoxicity in gastric cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway. | 2018 |
3 |
| 33 |
28296564 | AZD1775 induces toxicity through double-stranded DNA breaks independently of chemotherapeutic agents in p53-mutated colorectal cancer cells. | 2017 |
1 |
| 34 |
28349835 | The role of epithelial cell adhesion molecule N-glycosylation on apoptosis in breast cancer cells. | 2017 Mar |
1 |
| 35 |
28440463 | Livin enhances chemoresistance in head and neck squamous cell carcinoma. | 2017 Jun |
1 |
| 36 |
28454373 | Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway. | 2017 Apr |
1 |
| 37 |
28599477 | Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cells in vitro and in vivo. | 2017 Jun |
1 |
| 38 |
28870916 | GRP78 Regulates Apoptosis, Cell Survival and Proliferation in 5-Fluorouracil-resistant SNUC5 Colon Cancer Cells. | 2017 Sep |
1 |
| 39 |
29209153 | RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition. | 2017 |
1 |
| 40 |
26392056 | Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. | 2016 Aug 2 |
1 |
| 41 |
26432329 | Silencing of FGFR4 could influence the biological features of gastric cancer cells and its therapeutic value in gastric cancer. | 2016 Mar |
1 |
| 42 |
26462739 | Melatonin sensitizes human cervical cancer HeLa cells to cisplatin-induced cytotoxicity and apoptosis: effects on oxidative stress and DNA fragmentation. | 2016 Jan |
1 |
| 43 |
26505786 | Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways. | 2016 Jan 11 |
1 |
| 44 |
26662569 | The over-expression of FGFR4 could influence the features of gastric cancer cells and inhibit the efficacy of PD173074 and 5-fluorouracil towards gastric cancer. | 2016 May |
1 |
| 45 |
26691280 | Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation. | 2016 Feb |
2 |
| 46 |
26735343 | Comparative evaluation of PLGA nanoparticle delivery system for 5-fluorouracil and curcumin on squamous cell carcinoma. | 2016 Apr |
2 |
| 47 |
26810644 | Molecular targeted photoimmunotherapy for HER2-positive human gastric cancer in combination with chemotherapy results in improved treatment outcomes through different cytotoxic mechanisms. | 2016 Jan 25 |
2 |
| 48 |
26844701 | Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach. | 2016 Feb 4 |
2 |
| 49 |
26845645 | miR-450b-5p Suppresses Stemness and the Development of Chemoresistance by Targeting SOX2 in Colorectal Cancer. | 2016 May |
2 |
| 50 |
26893778 | Downregulation of Foxc2 enhances apoptosis induced by 5-fluorouracil through activation of MAPK and AKT pathways in colorectal cancer. | 2016 Feb |
1 |