Title : Downregulation of Foxc2 enhances apoptosis induced by 5-fluorouracil through activation of MAPK and AKT pathways in colorectal cancer.

Pub. Date : 2016 Feb

PMID : 26893778






1 Functional Relationships(s)
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1 Therefore, the downregulation of Foxc2, induced by 5-FU, may enhance apoptosis by the downregulation of apoptotic factors, including B cell lymphoma-2 and pro-caspase-3, in Foxc2-shRNA CRC cells. Fluorouracil caspase 3 Homo sapiens