Title : Loss of tumor intrinsic PD-L1 confers resistance to drug-induced apoptosis in human colon cancer.

Pub. Date : 2021 Jan

PMID : 33030957






2 Functional Relationships(s)
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1 Knockout of PD-L1 was shown to attenuate the induction of DNA double-strand breaks (pH2AX) and caspase-3 cleavage by 5-fluorouracil (5-FU) and paclitaxel compared to parental CRC cells. Fluorouracil caspase 3 Homo sapiens
2 Knockout of PD-L1 was shown to attenuate the induction of DNA double-strand breaks (pH2AX) and caspase-3 cleavage by 5-fluorouracil (5-FU) and paclitaxel compared to parental CRC cells. Fluorouracil caspase 3 Homo sapiens