Title : Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach.

Pub. Date : 2016 Feb 4

PMID : 26844701






2 Functional Relationships(s)
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1 Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach. Fluorouracil caspase 3 Homo sapiens
2 Exposure of explant cultures to 5FU-based CT increased the percentage of cells positive for active Caspase-3 and Terminal Deoxynucleotidyl Transferase dUTP Nick end Labelling (TUNEL), but also the expression of regeneration and proliferation markers beta-Catenin and Ki-67, as well as cyclooxygenase-2 (COX-2). Fluorouracil caspase 3 Homo sapiens