Pub. Date : 2017 Jul
PMID : 27859591
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using siRNAs, p38, JNK, PKCalpha, and PKCdelta, as well as ROS scavengers, it was observed that the dependence of PKCalpha/PKCdelta on ROS production to enhance JNK and p38 phosphorylation mediated HG-induced cardiac Nrf2 expression and activation. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Rattus norvegicus |
| 2 | Our study demonstrated that HG-induced cardiac Nrf2 activation occurs through PKCalpha/PKCdelta-ROS-JNK/p38 signaling. | Reactive Oxygen Species | mitogen-activated protein kinase 8 | Rattus norvegicus |