Everolimus

CREB regulated transcription coactivator 1 ; Mus musculus







102 Article(s)
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1 34261913 Norcantharidin counteracts acquired everolimus resistance in renal cell carcinoma by dual inhibition of mammalian target of rapamycin complex 1 and complex 2 pathways in Vitro. 2022 Jan 1 4
2 35136028 Exosome-mediated miR-7-5p delivery enhances the anticancer effect of Everolimus via blocking MNK/eIF4E axis in non-small cell lung cancer. 2022 Feb 8 1
3 33574130 Silencing of SmgGDS, a Novel mTORC1 Inducer That Binds to RHEBs, Inhibits Malignant Mesothelioma Cell Proliferation. 2021 May 1
4 33727259 Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations. 2021 Jul 15 1
5 33785482 Impact of Baseline and On-Treatment Glycemia on Everolimus-Exemestane Efficacy in Patients with Hormone Receptor-Positive Advanced Breast Cancer (EVERMET). 2021 Jun 15 1
6 33804593 PTEN R130Q Papillary Tumor of the Pineal Region (PTPR) with Chromosome 10 Loss Successfully Treated with Everolimus: A Case Report. 2021 Mar 20 1
7 33889306 High in vitro and in vivo synergistic activity between mTORC1 and PLK1 inhibition in adenocarcinoma NSCLC. 2021 Apr 13 2
8 33931486 Cutting Edge: mTORC1 Inhibition in Metastatic Breast Cancer Patients Negatively Affects Peripheral NK Cell Maturation and Number. 2021 May 15 1
9 34045438 Cyst(e)ine in nutrition formulation promotes colon cancer growth and chemoresistance by activating mTORC1 and scavenging ROS. 2021 May 28 1
10 34224367 Phase 0 Clinical Trial of Everolimus in Patients with Vestibular Schwannoma or Meningioma. 2021 Sep 2
11 34640378 Complete Purging of Ewing Sarcoma Metastases from Human Ovarian Cortex Tissue Fragments by Inhibiting the mTORC1 Signaling Pathway. 2021 Sep 24 1
12 34648891 Novel polymer-based system for intrauterine delivery of everolimus for anti-cancer applications. 2021 Nov 10 1
13 34959437 Therapeutic Response of CCKBR-Positive Tumors to Combinatory Treatment with Everolimus and the Radiolabeled Minigastrin Analogue [177Lu]Lu-PP-F11N. 2021 Dec 15 1
14 31463638 The tumor suppressor NDRG2 cooperates with an mTORC1 inhibitor to suppress the Warburg effect in renal cell carcinoma. 2020 Aug 2
15 31597506 Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus. 2020 1
16 31879363 Targeting Phosphorylation of Y-Box-Binding Protein YBX1 by TAS0612 and Everolimus in Overcoming Antiestrogen Resistance. 2020 Mar 1
17 32215854 Changes in PCSK9 and LDL cholesterol concentrations by everolimus treatment and their effects on polymorphisms in PCSK9 and mTORC1. 2020 Jun 4
18 32252811 Everolimus versus alpelisib in advanced hormone receptor-positive HER2-negative breast cancer: targeting different nodes of the PI3K/AKT/mTORC1 pathway with different clinical implications. 2020 Apr 6 3
19 32393148 PKG1α Cysteine-42 Redox State Controls mTORC1 Activation in Pathological Cardiac Hypertrophy. 2020 Jul 31 1
20 32411241 AdipoRon Affects Cell Cycle Progression and Inhibits Proliferation in Human Osteosarcoma Cells. 2020 1
21 32716476 The rapamycin analog Everolimus reversibly impairs male germ cell differentiation and fertility in the mouse†. 2020 Oct 29 1
22 32759497 Selective inhibition of mTORC1 in tumor vessels increases antitumor immunity. 2020 Aug 6 4
23 33079326 Follicle inhibition at the primordial stage without increasing apoptosis, with a combination of everolimus, verapamil. 2020 Nov 1
24 33182575 Early Changes of the Standardized Uptake Values (SUVmax) Predict the Efficacy of Everolimus-Exemestane in Patients with Hormone Receptor-Positive Metastatic Breast Cancer. 2020 Nov 10 1
25 30528247 Corrigendum to "Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway" [J. Neuroimmunol. 299 (2016) 164-171]. 2019 Jan 15 1
26 30682771 mTOR Inhibitors in Advanced Biliary Tract Cancers. 2019 Jan 24 1
27 30712550 Duplicate - Corrigendum to "Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway" [J. Neuroimmunol. 299 (2016) 164-171]. 2019 Feb 15 1
28 30796356 mTORC1 inhibitor RAD001 (everolimus) enhances non-small cell lung cancer cell radiosensitivity in vitro via suppressing epithelial-mesenchymal transition. 2019 Aug 1
29 31030237 Vitamin D increases glucocorticoid efficacy via inhibition of mTORC1 in experimental models of multiple sclerosis. 2019 Sep 1
30 31116586 Everolimus induces G1 cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells. 2019 Aug 1 3
31 31465093 Fulvestrant Plus Vistusertib vs Fulvestrant Plus Everolimus vs Fulvestrant Alone for Women With Hormone Receptor-Positive Metastatic Breast Cancer: The MANTA Phase 2 Randomized Clinical Trial. 2019 Nov 1 1
32 29121714 Everolimus Plus Ku0063794 Regimen Promotes Anticancer Effects against Hepatocellular Carcinoma Cells through the Paradoxical Inhibition of Autophagy. 2018 Jul 1
33 29251327 Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib. 2018 Feb 5
34 29428724 Dual inhibition of mTORC1 and mTORC2 perturbs cytoskeletal organization and impairs endothelial cell elongation. 2018 Feb 26 1
35 29507656 Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer. 2018 Feb 6 1
36 29557694 Lenvatinib in the management of metastatic renal cell carcinoma: a promising combination therapy? 2018 Apr 1
37 29720580 Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC). 2018 May 3 2
38 29880014 Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer. 2018 Jun 8 1
39 29895527 The role of GSK3 and its reversal with GSK3 antagonism in everolimus resistance. 2018 Oct 1
40 30104176 A Novel Combination of the mTORC1 Inhibitor Everolimus and the Immunomodulatory Drug Lenalidomide Produces Durable Responses in Patients With Heavily Pretreated Relapsed Lymphoma. 2018 Oct 1
41 30160042 Novel therapeutic roles of MC-4 in combination with everolimus against advanced renal cell carcinoma by dual targeting of Akt/pyruvate kinase muscle isozyme M2 and mechanistic target of rapamycin complex 1 pathways. 2018 Oct 2
42 30297804 MNK1 inhibitor CGP57380 overcomes mTOR inhibitor-induced activation of eIF4E: the mechanism of synergic killing of human T-ALL cells. 2018 Dec 1
43 30410117 A rapamycin derivative, biolimus, preferentially activates autophagy in vascular smooth muscle cells. 2018 Nov 8 1
44 30456298 mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential. 2018 1
45 27513674 Inhibition of mTOR's Catalytic Site by PKI-587 Is a Promising Therapeutic Option for Gastroenteropancreatic Neuroendocrine Tumor Disease. 2017 1
46 27935857 Potentiation of the anticancer effects of everolimus using a dual mTORC1/2 inhibitor in hepatocellular carcinoma cells. 2017 Jan 10 1
47 28211162 Efficacy of the oral mTORC1 inhibitor everolimus in relapsed or refractory indolent lymphoma. 2017 May 2
48 28270607 mTORC1/2 inhibition preserves ovarian function and fertility during genotoxic chemotherapy. 2017 Mar 21 1
49 28544747 K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines. 2017 Sep 1
50 28658205 mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. 2017 Jul 6 1