Title : Fulvestrant Plus Vistusertib vs Fulvestrant Plus Everolimus vs Fulvestrant Alone for Women With Hormone Receptor-Positive Metastatic Breast Cancer: The MANTA Phase 2 Randomized Clinical Trial.

Pub. Date : 2019 Nov 1

PMID : 31465093






1 Functional Relationships(s)
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1 Everolimus inhibits the mammalian target of rapamycin complex 1 (mTORC1) complex but not mTORC2, which can set off an activating feedback loop via mTORC2. Everolimus CREB regulated transcription coactivator 1 Mus musculus