3-methyladenine

mechanistic target of rapamycin kinase ; Homo sapiens







20 Article(s)
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1 35341775 Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts. 2022 Jun 1 2
2 33777755 The Local Anesthetic Bupivacaine Inhibits the Progression of Non-Small Cell Lung Cancer by Inducing Autophagy Through Akt/mTOR Signaling. 2021 2
3 33978839 Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway. 2021 Aug 2
4 34484820 miR-149 Alleviates Ox-LDL-Induced Endothelial Cell Injury by Promoting Autophagy through Akt/mTOR Pathway. 2021 2
5 34734026 Induction of osteoclast formation by LOX mutant (LOXG473A) through regulation of autophagy. 2021 Sep 1
6 31696568 Suppression of AMP-activated protein kinase reverses osteoprotegerin-induced inhibition of osteoclast differentiation by reducing autophagy. 2020 Jan 1
7 31931659 Autophagy drives fibroblast senescence through MTORC2 regulation. 2020 Nov 1
8 32319603 ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells. 2020 May 2
9 32691991 Puerarin 6″-O-xyloside suppressed HCC via regulating proliferation, stemness, and apoptosis with inhibited PI3K/AKT/mTOR. 2020 Sep 1
10 30897708 CLE-10 from Carpesium abrotanoides L. Suppresses the Growth of Human Breast Cancer Cells (MDA-MB-231) In Vitro by Inducing Apoptosis and Pro-Death Autophagy Via the PI3K/Akt/mTOR Signaling Pathway. 2019 Mar 20 2
11 31277013 Inhibition of Autophagy Attenuated Intestinal Injury After Intestinal I/R via mTOR Signaling. 2019 Nov 2
12 31497240 Babaodan inhibits cell growth by inducing autophagy through the PI3K/AKT/mTOR pathway and enhances antitumor effects of cisplatin in NSCLC cells. 2019 1
13 30170968 Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury. 2018 Sep 1
14 30416863 URI knockdown induces autophagic flux in gastric cancer cells. 2018 1
15 28528119 Autophagy plays a dual role during intracellular siRNA delivery by lipoplex and polyplex nanoparticles. 2017 Aug 3
16 27779641 AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. 2016 Dec 1
17 23813779 Tanshinone IIA induces autophagic cell death via activation of AMPK and ERK and inhibition of mTOR and p70 S6K in KBM-5 leukemia cells. 2014 Mar 1
18 24319109 Differential induction of autophagy by mTOR is associated with abnormal apoptosis in ovarian endometriotic cysts. 2014 Apr 1
19 24890505 Role of autophagy and mTOR signaling in neural differentiation of bone marrow mesenchymal stem cells. 2014 Nov 2
20 23794518 Autophagy stimulates apoptosis in HER2-overexpressing breast cancers treated by lapatinib. 2013 Dec 1