Title : Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway.

Pub. Date : 2021 Aug

PMID : 33978839






2 Functional Relationships(s)
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1 Apatinib inhibited the PI3K/Akt/mTOR pathway, while 3-MA and the combination of 3-MA and apatinib significantly activated the PI3K/Akt/mTOR pathway and inhibited autophagy. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens
2 Apatinib inhibited the PI3K/Akt/mTOR pathway, while 3-MA and the combination of 3-MA and apatinib significantly activated the PI3K/Akt/mTOR pathway and inhibited autophagy. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens