Title : Autophagy plays a dual role during intracellular siRNA delivery by lipoplex and polyplex nanoparticles.

Pub. Date : 2017 Aug

PMID : 28528119






3 Functional Relationships(s)
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1 Specifically, the mTOR-dependent autophagy inducer rapamycin enhanced the knockdown efficiency of both lipoplex and polyplex, whereas mTOR-dependent autophagy inhibitor 3-methyladenine (3-MA) suppressed their silencing efficiency. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens
2 Specifically, the mTOR-dependent autophagy inducer rapamycin enhanced the knockdown efficiency of both lipoplex and polyplex, whereas mTOR-dependent autophagy inhibitor 3-methyladenine (3-MA) suppressed their silencing efficiency. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens
3 Specifically, the mTOR-dependent autophagy inducer rapamycin enhances the knockdown efficiency of both lipoplex and polyplex, whereas mTOR-dependent autophagy inhibitor 3-methyladenine suppresses their silencing efficiency. 3-methyladenine mechanistic target of rapamycin kinase Homo sapiens