Title : The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

Pub. Date : 1997 Sep 25

PMID : 9380409






1 Functional Relationships(s)
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1 Here we show that induction of PT is sufficient to activate CPP32-like proteases with DEVDase activity and the associated cleavage of the nuclear DEVDase substrate poly(ADP-ribose) polymerase (PARP). Platinum poly(ADP-ribose) polymerase 1 Homo sapiens