| 1 |
35147740 | Prediction of drug-drug interaction potential mediated by transporters between dasatinib and metformin, pravastatin, and rosuvastatin using physiologically based pharmacokinetic modeling. | 2022 Mar |
1 |
| 2 |
31699807 | Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma. | 2020 Jan |
1 |
| 3 |
31881192 | Interaction of Oatp1b2 expression and nonalcoholic steatohepatitis on pravastatin plasma clearance. | 2020 Apr |
1 |
| 4 |
32892153 | Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport. | 2020 Nov |
1 |
| 5 |
30318712 | Effects of Uremic Serum Residue on OATP1B1- and OATP1B3-Mediated Pravastatin Uptake in OATP-Expressing HEK293 Cells and Human Hepatocytes. | 2019 Apr |
1 |
| 6 |
30549267 | Impact of Genetic Variation on Pravastatin Systemic Exposure in Pediatric Hypercholesterolemia. | 2019 Jun |
3 |
| 7 |
30652318 | Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes. | 2019 Feb |
2 |
| 8 |
30982223 | Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers. | 2019 Jul |
2 |
| 9 |
31047942 | Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions. | 2019 Oct |
1 |
| 10 |
29786857 | Effect of OATP1B1/1B3 Inhibitor GDC-0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects. | 2018 Nov |
2 |
| 11 |
30335192 | Assessment of OATP transporter-mediated drug-drug interaction using physiologically-based pharmacokinetic (PBPK) modeling - a case example. | 2018 Nov |
1 |
| 12 |
27619346 | Feasibility of the functional expression of the human organic anion transporting polypeptide 1B1 (OATP1B1) and its genetic variant 521T/C in the mouse liver. | 2017 Jan 1 |
1 |
| 13 |
26744986 | Mixed effects of OATP1B1, BCRP and NTCP polymorphisms on the population pharmacokinetics of pravastatin in healthy volunteers. | 2016 Sep |
1 |
| 14 |
26826613 | Effects of the SLCO1B1 *1 and SLCO1B1 *5 polymorphisms on IL-6 and IL-10 levels in patients under pravastatin treatment prior to inguinal hernia repair. | 2016 Mar |
1 |
| 15 |
27594653 | Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1). | 2016 Nov |
3 |
| 16 |
27631194 | Mapping SLCO1B1 Genetic Variation for Global Precision Medicine in Understudied Regions in Africa: A Focus on Zulu and Cape Admixed Populations. | 2016 Sep |
1 |
| 17 |
25379722 | Function-impairing polymorphisms of the hepatic uptake transporter SLCO1B1 modify the therapeutic efficacy of statins in a population-based cohort. | 2015 Jan |
1 |
| 18 |
25221728 | Pharmacogenetics of Statin-Induced Myopathy: A Focused Review of the Clinical Translation of Pharmacokinetic Genetic Variants. | 2014 Apr 23 |
1 |
| 19 |
25494035 | Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations. | 2014 Dec 10 |
1 |
| 20 |
25563221 | Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients. | 2014 Mar 27 |
1 |
| 21 |
22928802 | Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect. | 2013 Mar |
1 |
| 22 |
21623698 | Clinical response to statins: mechanism(s) of variable activity and adverse effects. | 2012 Aug |
2 |
| 23 |
21851379 | The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin. | 2012 Feb |
2 |
| 24 |
22114872 | Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment. | 2012 May |
5 |
| 25 |
22174437 | Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin. | 2012 Nov |
2 |
| 26 |
22189199 | Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly. | 2012 Feb |
2 |
| 27 |
22524173 | Role of genetic factors in statins side-effects. | 2012 Sep |
1 |
| 28 |
23082789 | Characterization of organic anion transporting polypeptide (OATP) expression and its functional contribution to the uptake of substrates in human hepatocytes. | 2012 Dec 3 |
1 |
| 29 |
23190519 | Influence of serum in hemodialysis patients on the expression of intestinal and hepatic transporters for the excretion of pravastatin. | 2012 Dec |
1 |
| 30 |
21297370 | [Genetic marker of statin-induced rhabdomyolysis]. | 2011 Feb |
1 |
| 31 |
21389119 | Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport. | 2011 Jun |
1 |
| 32 |
22216116 | Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. | 2011 |
3 |
| 33 |
21063755 | Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans. | 2010 Dec |
2 |
| 34 |
19001154 | Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans. | 2009 Feb |
2 |
| 35 |
19238167 | Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy. | 2009 Jun |
6 |
| 36 |
19776292 | Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic Information on SLCO1B1 and ABCC2 polymorphisms. | 2009 Nov |
2 |
| 37 |
18408565 | The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15. | 2008 May |
11 |
| 38 |
18413659 | Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin. | 2008 Aug |
1 |
| 39 |
18641915 | Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism. | 2008 |
1 |
| 40 |
17177112 | Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans. | 2007 Feb |
11 |
| 41 |
17296622 | The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. | 2007 May |
2 |
| 42 |
17439540 | SLCO1B1 521T-->C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients. | 2007 Sep |
8 |
| 43 |
17470528 | Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. | 2007 Aug |
1 |
| 44 |
17523051 | Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1. | 2007 May |
4 |
| 45 |
17622941 | Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants. | 2007 Aug |
5 |
| 46 |
16568260 | Influence of the SLCO1B1*1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels. | 2006 Apr |
3 |
| 47 |
16678544 | Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin. | 2006 May |
4 |
| 48 |
16678545 | Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril. | 2006 May |
2 |
| 49 |
16722833 | Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes. | 2006 Jun |
5 |
| 50 |
16917677 | Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy. | 2006 |
3 |