Pravastatin

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







64 Article(s)
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51 17015053 SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin. 2006 Oct 4
52 17047488 Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics. 2006 Nov 3
53 15608127 Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. 2005 Mar 1
54 15864131 Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17. 2005 May 7
55 15970799 Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells. 2005 Jul 4
56 16180115 Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. 2005 Oct 3
57 15096102 Pharmacokinetics of flunixin in the cat: enterohepatic circulation and active transport mechanism in the liver. 2004 Apr 2
58 15116054 Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. 2004 May 4
59 15226675 High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1). 2004 Jul 4
60 15681900 A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy. 2004 Dec 3
61 12811365 Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. 2003 Jun 5
62 11748225 Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). 2002 Feb 22 1
63 11356905 Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. 2001 Jun 1
64 10601278 A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. 1999 Dec 24 1