Glycyrrhetinic Acid

hydroxysteroid 11-beta dehydrogenase 2 ; Homo sapiens







26 Article(s)
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1 31915940 Food Products That May Cause an Increase in Blood Pressure. 2020 Jan 8 2
2 32574273 Symptomatic Protective Action of Glycyrrhizin (Licorice) in COVID-19 Infection? 2020 2
3 31379750 Licorice: From Pseudohyperaldosteronism to Therapeutic Uses. 2019 1
4 28624548 Glucocorticoids and gut bacteria: "The GALF Hypothesis" in the metagenomic era. 2017 Sep 2
5 24176792 An alternative explanation of hypertension associated with 17α-hydroxylase deficiency syndrome. 2014 Jan 1
6 24620820 Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature review. 2014 Jun 1
7 22543032 3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2. 2012 Aug 2
8 22850318 The effect of water loading on the urinary ratio of cortisone to cortisol in healthy subjects and a new approach to the evaluation of the ratio as an index for in vivo human 11β-hydroxysteroid dehydrogenase 2 activity. 2012 Oct 1
9 21184804 Liquorice and glycyrrhetinic acid increase DHEA and deoxycorticosterone levels in vivo and in vitro by inhibiting adrenal SULT2A1 activity. 2011 Apr 10 2
10 21236343 Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11β-hydroxysteroid dehydrogenase type 2. 2011 May 1
11 21376605 Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11β-hydroxysteroid dehydrogenase 2 inhibitors. 2011 Mar 15 1
12 21539886 Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione. 2011 Jul 1
13 20629036 Selection and optimization of MCF-7 cell line for screening selective inhibitors of 11beta-hydroxysteroid dehydrogenase 2. 2010 Aug 2
14 19789539 Licorice: a sweet alternative to prevent hyperkalemia in dialysis patients? 2009 Oct 1
15 17447595 [From gene to disease; 'apparent mineralocorticoid excess' syndrome, a syndrome with an apparent excess of mineral corticoids]. 2007 Mar 24 1
16 15631868 Use of 11alpha-deuterium labeled cortisol as a tracer for assessing reduced 11beta-HSD2 activity in vivo following glycyrrhetinic acid ingestion in a human subject. 2005 Feb 3
17 16005482 Validation of the plasma half-life of 11alpha-deuterium cortisol as a sensitive index for the analysis of human 11beta-HSD2 activity in vivo. 2005 Nov 1
18 12642869 Abnormal expression of 11 beta-hydroxysteroid dehydrogenase type 2 in human pituitary adenomas: a prereceptor determinant of pituitary cell proliferation. 2003 Mar 20 1
19 12911547 Angiotensin II regulates 11beta-hydroxysteroid dehydrogenase type 2 via AT2 receptors. 2003 Sep 2
20 11752037 Glycyrrhetinic acid decreases plasma potassium concentrations in patients with anuria. 2002 Jan 2
21 12239243 Modulation of renal calcium handling by 11 beta-hydroxysteroid dehydrogenase type 2. 2002 Oct 1
22 11604236 Modulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity in Ishikawa cells is associated with changes in cellular proliferation. 2001 Oct 25 1
23 11751713 In vivo 11beta-HSD-2 activity: variability, salt-sensitivity, and effect of licorice. 2001 Dec 1 1
24 9453347 Impact of dietary Na+ on glycyrrhetinic acid-like factors (kidney 11beta-(HSD2)-GALFs) in human essential hypertension. 1998 Jan 1
25 9683905 The role of 11 beta-hydroxysteroid dehydrogenase in the pathogenesis of hypertension. 1998 Apr 1
26 9029719 Human 11 beta-hydroxysteroid dehydrogenase: studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue. 1997 Jan 4