Superoxides

NADPH oxidase 1 ; Homo sapiens







70 Article(s)
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1 35358850 The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner. 2022 Jun 1
2 33548451 Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. 2021 Mar 2
3 33932953 Oxidant-resistant LRRC8A/C anion channels support superoxide production by NADPH oxidase 1. 2021 Jun 4
4 34164520 Attenuating glucose metabolism by Fbxw7 promotes Taxol sensitivity of colon cancer cells through downregulating NADPH oxidase 1 (Nox1). 2021 May 2
5 32924676 Constitutive activity of NADPH oxidase 1 (Nox1) that promotes its own activity suppresses the colon epithelial cell migration. 2020 Sep 2
6 30760703 Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas. 2019 Feb 13 3
7 30889865 Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR). 2019 Mar 18 1
8 30925081 Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis. 2019 Jun 1 1
9 29156213 HOCl and the control of oncogenesis. 2018 Feb 1
10 29718541 Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar1. 2018 Jun 1
11 29262595 Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway. 2017 Nov 28 2
12 27094494 Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration. 2016 Jul 3
13 27497729 β-eudesmol, a sesquiterpene from Teucrium ramosissimum, inhibits superoxide production, proliferation, adhesion and migration of human tumor cell. 2016 Sep 1
14 27838438 LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis. 2016 Dec 7
15 27874952 Nox1 promotes colon cancer cell metastasis via activation of the ADAM17 pathway. 2016 Nov 2
16 29431084 Nitric Oxide's Contribution to Selective Apoptosis Induction in Malignant Cells through Multiple Reaction Steps. 2016 1
17 25619142 Revealing mechanisms of selective, concentration-dependent potentials of 4-hydroxy-2-nonenal to induce apoptosis in cancer cells through inactivation of membrane-associated catalase. 2015 Apr 1
18 25893083 The role of excitotoxic programmed necrosis in acute brain injury. 2015 1
19 26001727 c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells. 2015 Sep 1
20 26065917 NADPH oxidase activation contributes to native low-density lipoprotein-induced proliferation of human aortic smooth muscle cells. 2015 Jun 12 2
21 26504017 Intercellular HOCl-mediated Apoptosis Induction in Malignant Cells: Interplay Between NOX1-Dependent Superoxide Anion Generation and DUOX-related HOCl-generating Peroxidase Activity. 2015 Nov 1
22 24365146 N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1. 2014 Jan 17 4
23 24692674 Targeting extracellular ROS signaling of tumor cells. 2014 Apr 2
24 25062272 Nox4: a hydrogen peroxide-generating oxygen sensor. 2014 Aug 12 1
25 25066192 Endothelial NADPH oxidases: which NOX to target in vascular disease? 2014 Sep 1
26 22937798 Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress. 2013 Apr 20 1
27 23957209 Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1. 2013 Oct 4
28 24187133 Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration. 2013 Dec 20 6
29 22098189 NADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's disease. 2012 May 15 1
30 22158615 Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. 2012 Jan 27 1
31 22753718 Tumor cell-protective catalase as a novel target for rational therapeutic approaches based on specific intercellular ROS signaling. 2012 Jul 2
32 21194376 Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production. 2011 Jun 1
33 21343298 The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. 2011 Apr 15 2
34 19875720 HO-1 and CO decrease platelet-derived growth factor-induced vascular smooth muscle cell migration via inhibition of Nox1. 2010 Jan 1
35 20171273 Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis. 2010 May 15 1
36 20454568 Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1. 2010 May 4 1
37 20679349 A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase. 2010 Oct 8 1
38 19061439 Identification of structural elements in Nox1 and Nox4 controlling localization and activity. 2009 Jun 1
39 19438290 Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases. 2009 Oct 1
40 19451223 NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/alpha3 integrins. 2009 Jul 2
41 19671250 Overexpression of the superoxide anion and NADPH oxidase isoforms 1 and 4 (NOX1 and NOX4) in allergic nasal mucosa. 2009 Jul-Aug 2
42 19714290 Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon. 2009 1
43 18023288 Nox1-dependent superoxide production controls colon adenocarcinoma cell migration. 2008 Jan 8
44 18035043 Ionizing irradiation induces apoptotic damage of salivary gland acinar cells via NADPH oxidase 1-dependent superoxide generation. 2008 Feb 8 1
45 18398843 Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras. 2008 Jul 1 2
46 18518859 Activation of NADPH oxidase 1 in tumour colon epithelial cells. 2008 Oct 1 1
47 18625439 Reactive oxygen species generation at the plasma membrane for antibody control. 2008 Jul 1
48 16963617 Autocrine/paracrine pattern of superoxide production through NAD(P)H oxidase in coronary arterial myocytes. 2007 Jan 2
49 17460729 Nox1 induces differentiation resistance in immortalized human keratinocytes generating cells that express simple epithelial keratins. 2007 Sep 3
50 17462535 Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. 2007 Jun 1 1