Pub. Date : 2008 Jan
PMID : 18023288
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nox1-dependent superoxide production controls colon adenocarcinoma cell migration. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 2 | These new homologues (Nox1-Nox5) produce low levels of superoxides compared to the phagocytic homologue Nox2/gp91phox. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 3 | Using Nox1 siRNA, we show that Nox1-dependent superoxide production affects the migration of HT29-D4 colonic adenocarcinoma cells on collagen-I. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 4 | Using Nox1 siRNA, we show that Nox1-dependent superoxide production affects the migration of HT29-D4 colonic adenocarcinoma cells on collagen-I. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 5 | Nox1 inhibition or down-regulation led to a decrease of superoxide production and alpha 2 beta 1 integrin membrane availability. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 6 | An addition of arachidonic acid stimulated Nox1-dependent superoxide production and HT29-D4 cell migration. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 7 | Inhibition of 12-lipoxygenase decreased basal and arachidonic acid induced Nox1-dependent superoxide production and cell migration. | Superoxides | NADPH oxidase 1 | Homo sapiens |
| 8 | Protein kinase C delta inhibition by rottlerin (and also GO6983) prevented Nox1-dependent superoxide production and inhibited cell migration, while other protein kinase C inhibitors were ineffective. | Superoxides | NADPH oxidase 1 | Homo sapiens |