Title : Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis.

Pub. Date : 2010 May 15

PMID : 20171273






1 Functional Relationships(s)
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1 Here, to further investigate the role of HIPK2 in p53 activation, we started with the finding that HIPK2 inhibition upregulated Nox1, a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase, involved in tumor progression and ROS production. Superoxides NADPH oxidase 1 Homo sapiens