2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

BCL2 associated X, apoptosis regulator ; Homo sapiens







29 Article(s)
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1 34558536 Baicalin attenuates blood-spinal cord barrier disruption and apoptosis through PI3K/Akt signaling pathway after spinal cord injury. 2022 May 1
2 33846811 Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells. 2021 Jun 1
3 34339756 DG-8d, a novel diosgenin derivative, decreases the proliferation and induces the apoptosis of A549 cells by inhibiting the PI3k/Akt signaling pathway. 2021 Oct 1
4 34697781 Jolkinolide B attenuates laryngeal cancer cell growth and induces apoptosis via PTEN/PI3K/Akt signaling pathway. 2021 Sep 1
5 32691555 [Nano-silicon Dioxide Affects Apoptosis of Alveolar Macrophages via PI3K/AKt Signaling Pathway]. 2020 Jul 1
6 32922037 CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling. 2020 1
7 31786865 Apatinib suppresses the Proliferation and Apoptosis of Gastric Cancer Cells via the PI3K/Akt Signaling Pathway. 2019 Sep-Oct 2
8 29496475 PI3K signaling pathways modulated white spot syndrome virus (WSSV) replication in Procambarus clarkii. 2018 May 3
9 30240165 Bi2 S3 -Tween 20 Nanodots Loading PI3K Inhibitor, LY294002, for Mild Photothermal Therapy of LoVo Cells In Vitro and In Vivo. 2018 Nov 1
10 30259565 Sodium butyrate ameliorates lipopolysaccharide-induced cow mammary epithelial cells from oxidative stress damage and apoptosis. 2018 Sep 26 1
11 28731179 Clinical significance of miR-138 in patients with malignant melanoma through targeting of PDK1 in the PI3K/AKT autophagy signaling pathway. 2017 Sep 1
12 28789432 Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer. 2017 Aug 1
13 25212570 Down-regulation of Akt by methanol extracts of Impatiens balsamina L. promotes apoptosis in human oral squamous cell carcinoma cell lines. 2015 Jul 1
14 25510413 Survival-apoptosis associated signaling in GNE myopathy-cultured myoblasts. 2015 2
15 25938832 [Role of PI3K/Akt pathway in endoplasmic reticulum stress and apoptosis induced by saturated fatty acid in human steatotic hepatocytes]. 2015 Mar 1
16 26256949 Hypoxia-mediated cancer stem cells in pseudopalisades with activation of hypoxia-inducible factor-1α/Akt axis in glioblastoma. 2015 Oct 1
17 23910058 In vitro regulation of hepatocellular carcinoma cell viability, apoptosis, invasion, and AEG-1 expression by LY294002. 2014 Feb 1
18 23361188 17β-estradiol impedes Bax-involved mitochondrial apoptosis of retinal nerve cells induced by oxidative damage via the phosphatidylinositol 3-kinase/Akt signal pathway. 2013 Jul 1
19 23743572 Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine. 2013 Aug 1
20 21130731 Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2. 2011 Feb 18 2
21 21320517 The neuroprotective action of pyrroloquinoline quinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway. 2011 Apr 1 1
22 19278624 Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation. 2009 May 2
23 19051078 Phosphoinositide 3-kinase/Akt signalling is responsible for the differential susceptibility of myoblasts and myotubes to menadione-induced oxidative stress. 2008 Sep 1
24 16767165 Epidermal growth factor and serum activate distinct pathways to inhibit the BH3 only protein BAD in prostate carcinoma LNCaP cells. 2006 Jul 27 1
25 15642728 Nicotine inactivation of the proapoptotic function of Bax through phosphorylation. 2005 Mar 18 1
26 15942663 GSK-3beta reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis. 2005 Jul 1
27 16162974 Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria. 2005 Oct 1
28 12879014 Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited. 2003 Jul 24 1
29 11842081 The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. 2002 Apr 19 3