Pub. Date : 2002 Apr 19
PMID : 11842081
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We found that LY294002, a PI3K inhibitor, blocked the effects of serum to prevent Bax translocation to mitochondria and that expression of an active form of PI3K suppressed staurosporine-induced Bax translocation, suggesting that PI3K activity is essential for retaining Bax in the cytoplasm. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | BCL2 associated X, apoptosis regulator | Homo sapiens |
2 | We found that LY294002, a PI3K inhibitor, blocked the effects of serum to prevent Bax translocation to mitochondria and that expression of an active form of PI3K suppressed staurosporine-induced Bax translocation, suggesting that PI3K activity is essential for retaining Bax in the cytoplasm. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | BCL2 associated X, apoptosis regulator | Homo sapiens |
3 | We found that LY294002, a PI3K inhibitor, blocked the effects of serum to prevent Bax translocation to mitochondria and that expression of an active form of PI3K suppressed staurosporine-induced Bax translocation, suggesting that PI3K activity is essential for retaining Bax in the cytoplasm. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | BCL2 associated X, apoptosis regulator | Homo sapiens |