Title : In vitro regulation of hepatocellular carcinoma cell viability, apoptosis, invasion, and AEG-1 expression by LY294002.

Pub. Date : 2014 Feb

PMID : 23910058






1 Functional Relationships(s)
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1 Molecularly, LY294002 treatment down-regulated AEG-1 expression, AKT and GSK3beta phosphorylation, and expression of cyclinD1, CDK4, VEGF and Bcl2, but up-regulated Bax and c-Myc expression. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one BCL2 associated X, apoptosis regulator Homo sapiens