Epoprostenol

prostaglandin-endoperoxide synthase 1 ; Homo sapiens







32 Article(s)
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1 35259564 Contribution of cyclooxygenase-1-dependent prostacyclin synthesis to bradykinin-induced dermal extravasation. 2022 Apr 1
2 31628732 A novel single-chain enzyme complex with chain reaction properties rapidly producing thromboxane A2 and exhibiting powerful anti-bleeding functions. 2019 Dec 3
3 27381367 The principal pathways involved in the in vivo modulation of hypoxic pulmonary vasoconstriction, pulmonary arterial remodelling and pulmonary hypertension. 2017 Apr 1
4 26151307 Involvement of prostaglandin I(2) in nitric oxide-induced vasodilation of retinal arterioles in rats. 2015 Oct 5 2
5 23319543 Estradiol-17β and its cytochrome P450- and catechol-O-methyltransferase-derived metabolites selectively stimulate production of prostacyclin in uterine artery endothelial cells: role of estrogen receptor-α versus estrogen receptor-β. 2013 Feb 1
6 21938725 Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells. 2012 Jul 1
7 22301626 Role of cyclooxygenase-1-mediated prostacyclin synthesis in endothelium-dependent vasoconstrictor activity of porcine interlobular renal arteries. 2012 May 1 1
8 23045674 Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system. 2012 Oct 23 1
9 16533160 Implications of the molecular basis of prostacyclin biosynthesis and signaling in pharmaceutical designs. 2006 2
10 16581062 Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. 2006 May 1 2
11 16952710 Prostacyclin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 and cyclooxygenase inhibitors. 2006 Oct 1
12 15950656 Raloxifene promotes prostacyclin release in human endothelial cells through a mechanism that involves cyclooxygenase-1 and -2. 2005 Jun 1
13 15965079 Effect of enhanced prostacyclin synthesis by adenovirus-mediated transfer on lipopolysaccharide stimulation in neuron-glia cultures. 2005 May 2
14 16115891 Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells. 2005 Nov 4 1
15 14975458 Optimal suppression of thromboxane A(2) formation by aspirin during percutaneous transluminal coronary angioplasty: no additional effect of a selective cyclooxygenase-2 inhibitor. 2004 Feb 18 1
16 15001457 HDL3 induces cyclooxygenase-2 expression and prostacyclin release in human endothelial cells via a p38 MAPK/CRE-dependent pathway: effects on COX-2/PGI-synthase coupling. 2004 May 2
17 15458742 17beta-estradiol up-regulates prostacyclin production in cultured human uterine myometrial cells via augmentation of both cyclooxygenase-1 and prostacyclin synthase expression. 2004 Oct 1
18 12637362 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation. 2003 Jul 2
19 11145613 Angiotensin II as a trophic factor of white adipose tissue: stimulation of adipose cell formation. 2001 Jan 1
20 11319200 Selective augmentation of prostacyclin production by combined prostacyclin synthase and cyclooxygenase-1 gene transfer. 2001 Apr 24 4
21 11489432 Functional and cellular interactions between nitric oxide and prostacyclin. 2001 Aug 1
22 10809766 Colocalization of prostacyclin synthase with prostaglandin H synthase-1 (PGHS-1) but not phorbol ester-induced PGHS-2 in cultured endothelial cells. 2000 May 19 1
23 10821698 Fluorescence quenching analysis of the association and dissociation of a diarylheterocycle to cyclooxygenase-1 and cyclooxygenase-2: dynamic basis of cyclooxygenase-2 selectivity. 2000 May 23 1
24 10841038 Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells. 2000 Mar 1
25 10952950 Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Aug 22 1
26 11016419 Shear stress differentially regulates PGHS-1 and PGHS-2 protein levels in human endothelial cells. 2000 Jul 1
27 10664933 Expression of cyclooxygenase in nasal polyps from atopic and nonatopic subjects. 1999 Nov-Dec 1
28 10691023 The mechanism of thrombin-induced prostacyclin synthesis in human endothelial cells with reference to the gene transcription of prostacyclin-related enzymes and Ca2+ kinetics. 1999 Aug 1
29 9649571 Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium. 1998 Jul 1 5
30 7620513 Regulatory mechanisms of the vascular endothelium: an update. 1994 Nov-Dec 1
31 7977706 Kinetics of prostacyclin synthesis in PGHS-1-overexpressed endothelial cells. 1994 Nov 7
32 8473524 Enhanced prostacyclin synthesis in endothelial cells by retrovirus-mediated transfer of prostaglandin H synthase cDNA. 1993 Apr 3