Title : Stabilization of hypoxia-inducible factor-1{alpha} by prostacyclin under prolonged hypoxia via reducing reactive oxygen species level in endothelial cells.

Pub. Date : 2005 Nov 4

PMID : 16115891






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Augmentation of PGI(2) via adenovirus-mediated gene transfer of both cyclooxygenase-1 and PGI(2) synthase activated HIF-1 by stabilizing HIF-1alpha in cells under prolonged hypoxia or the hypoxia-normoxia transition but not under normoxia. Epoprostenol prostaglandin-endoperoxide synthase 1 Homo sapiens