| 1 |
34750622 | Reduced nuclear NAD+ drives DNA damage and subsequent immune activation in the retina. | 2022 May 4 |
3 |
| 2 |
35334034 | NAD+ centric mechanisms and molecular determinants of skeletal muscle disease and aging. | 2022 Jun |
1 |
| 3 |
35504207 | STING modulates necrotic cell death in CD4 T cells via activation of PARP-1/PAR following acute systemic inflammation. | 2022 Aug |
2 |
| 4 |
33563078 | Metabolomic and transcriptional profiling reveals bioenergetic stress and activation of cell death and inflammatory pathways in vivo after neuronal deletion of NAMPT. | 2021 Aug |
2 |
| 5 |
33609723 | Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis. | 2021 Apr |
1 |
| 6 |
34089817 | Modulation of NAD+ biosynthesis activates SIRT1 and resists cisplatin-induced ototoxicity. | 2021 Oct 1 |
2 |
| 7 |
34183378 | Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease. | 2021 Sep |
1 |
| 8 |
34343089 | Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication. | 2021 Aug 3 |
5 |
| 9 |
34374810 | The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells. | 2021 Nov |
2 |
| 10 |
32059481 | Identification of PARP-1, Histone H1 and SIRT-1 as New Regulators of Breast Cancer-Related Aromatase Promoter I.3/II. | 2020 Feb 12 |
10 |
| 11 |
32066462 | mTOR may interact with PARP-1 to regulate visible light-induced parthanatos in photoreceptors. | 2020 Feb 17 |
1 |
| 12 |
32278117 | Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction. | 2020 Jun |
2 |
| 13 |
32300965 | Aging alters acetylation status in skeletal and cardiac muscles. | 2020 Jun |
1 |
| 14 |
32344695 | Reduced Tumorigenicity of Mouse ES Cells and the Augmented Anti-Tumor Therapeutic Effects under Parg Deficiency. | 2020 Apr 24 |
1 |
| 15 |
32822587 | Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis. | 2020 Sep 17 |
3 |
| 16 |
33199755 | Metabolic interaction between amino acid deprivation and cisplatin synergistically reduces phosphoribosyl-pyrophosphate and augments cisplatin cytotoxicity. | 2020 Nov 16 |
1 |
| 17 |
30996287 | Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function. | 2019 Dec |
1 |
| 18 |
30996792 | Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. | 2019 Apr 11 |
1 |
| 19 |
31214115 | Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. | 2019 |
1 |
| 20 |
31353811 | Augmentation of cellular NAD+ by NQO1 enzymatic action improves age-related hearing impairment. | 2019 Oct |
2 |
| 21 |
31511627 | Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD). | 2019 Sep 11 |
2 |
| 22 |
31569682 | Spontaneous Development of Dental Dysplasia in Aged Parp-1 Knockout Mice. | 2019 Sep 27 |
1 |
| 23 |
31576091 | High mobility group box-1 release from H2O2-injured hepatocytes due to sirt1 functional inhibition. | 2019 Sep 28 |
2 |
| 24 |
31679124 | Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. | 2019 Oct |
6 |
| 25 |
31754701 | Overexpression of Sirtuin 1 protein in neurons prevents and reverses experimental diabetic neuropathy. | 2019 Dec 1 |
1 |
| 26 |
29317476 | Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Attenuated Hepatic Triglyceride Accumulation in Alcoholic Fatty Liver Disease in Mice. | 2018 Mar |
3 |
| 27 |
29636359 | Targeting NAD+/PARP DNA Repair Pathway as a Novel Therapeutic Approach to SDHB-Mutated Cluster I Pheochromocytoma and Paraganglioma. | 2018 Jul 15 |
1 |
| 28 |
29901258 | Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. | 2018 Aug |
2 |
| 29 |
30184433 | Synthesis and Evaluation of a Mitochondria-Targeting Poly(ADP-ribose) Polymerase-1 Inhibitor. | 2018 Oct 19 |
1 |
| 30 |
30291911 | Augmentation of NAD+ levels by enzymatic action of NAD(P)H quinone oxidoreductase 1 attenuates adriamycin-induced cardiac dysfunction in mice. | 2018 Nov |
2 |
| 31 |
30359575 | PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis. | 2018 Dec 15 |
1 |
| 32 |
27663419 | Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. | 2017 Jan |
8 |
| 33 |
27984176 | PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis. | 2017 Mar |
2 |
| 34 |
28095779 | Poly(ADP-ribose) polymerase inhibitors activate the p53 signaling pathway in neural stem/progenitor cells. | 2017 Jan 17 |
2 |
| 35 |
28336669 | A conserved NAD+ binding pocket that regulates protein-protein interactions during aging. | 2017 Mar 24 |
1 |
| 36 |
28537485 | The NAD+/PARP1/SIRT1 Axis in Aging. | 2017 Jun |
11 |
| 37 |
28543772 | PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS. | 2017 Sep |
6 |
| 38 |
28824383 | Selective Sparing of Striatal Interneurons after Poly (ADP-Ribose) Polymerase 1 Inhibition in the R6/2 Mouse Model of Huntington's Disease. | 2017 |
1 |
| 39 |
28970491 | Rev1 contributes to proper mitochondrial function via the PARP-NAD+-SIRT1-PGC1α axis. | 2017 Oct 2 |
2 |
| 40 |
29137352 | Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice. | 2017 Oct 13 |
1 |
| 41 |
26856538 | AMP-activated protein kinase contributes to zinc-induced neuronal death via activation by LKB1 and induction of Bim in mouse cortical cultures. | 2016 Feb 9 |
2 |
| 42 |
26912654 | Transcriptional Reprogramming and Resistance to Colonic Mucosal Injury in Poly(ADP-ribose) Polymerase 1 (PARP1)-deficient Mice. | 2016 Apr 22 |
1 |
| 43 |
27173464 | Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes. | 2016 Jun |
1 |
| 44 |
27567805 | Bioenergetic Impairment in Animal and Cellular Models of Alzheimer's Disease: PARP-1 Inhibition Rescues Metabolic Dysfunctions. | 2016 Aug 10 |
1 |
| 45 |
25517228 | Poly(ADP-ribose) polymerase 1-sirtuin 1 functional interplay regulates LPS-mediated high mobility group box 1 secretion. | 2015 Mar 12 |
3 |
| 46 |
25712525 | Zinc preconditioning protects against neuronal apoptosis through the mitogen-activated protein kinase-mediated induction of heat shock protein 70. | 2015 Apr 3 |
2 |
| 47 |
25788480 | Pharmacological NAD-Boosting Strategies Improve Mitochondrial Homeostasis in Human Complex I-Mutant Fibroblasts. | 2015 Jun |
3 |
| 48 |
26080614 | 3-aminobenzamide, a poly (ADP ribose) polymerase inhibitor, enhances wound healing in whole body gamma irradiated model. | 2015 Sep |
1 |
| 49 |
26218895 | Differentiation-Associated Downregulation of Poly(ADP-Ribose) Polymerase-1 Expression in Myoblasts Serves to Increase Their Resistance to Oxidative Stress. | 2015 |
2 |
| 50 |
24275857 | Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes. | 2014 Feb |
1 |