Pub. Date : 2017 Jan
PMID : 27663419
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 2 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 3 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 4 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 5 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 6 | METHODS: As poly ADP-ribosylation (PARylation) of proteins by PARPs consumes nicotinamide adenine dinucleotide (NAD+), we hypothesized that overactivation of PARPs drives NAD+ depletion in NAFLD. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 7 | Therefore, we assessed the effectiveness of PARP inhibition to replenish NAD+ and activate NAD+-dependent sirtuins, hence improving hepatic fatty acid oxidation. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |
| 8 | Therefore, we assessed the effectiveness of PARP inhibition to replenish NAD+ and activate NAD+-dependent sirtuins, hence improving hepatic fatty acid oxidation. | NAD | poly (ADP-ribose) polymerase family, member 1 | Mus musculus |