| 51 |
26700958 | Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1-Transfected Human Embryonic Kidney 293 Cells. | 2016 Mar |
2 |
| 52 |
26977146 | The Impacts of SLC22A1 rs594709 and SLC47A1 rs2289669 Polymorphisms on Metformin Therapeutic Efficacy in Chinese Type 2 Diabetes Patients. | 2016 |
2 |
| 53 |
27019345 | Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions. | 2016 Jun 10 |
2 |
| 54 |
27128732 | Early Discontinuation of Metformin in Individuals Treated with Inhibitors of Transporters of Metformin. | 2016 Jun |
1 |
| 55 |
27317943 | Polyspecific organic cation transporters and their impact on drug intracellular levels and pharmacodynamics. | 2016 Sep |
2 |
| 56 |
27386433 | Impact of ATM and SLC22A1 Polymorphisms on Therapeutic Response to Metformin in Iranian Diabetic Patients. | 2016 Winter |
1 |
| 57 |
27493135 | Effect of Serotonin Transporter 5-HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study. | 2016 Nov |
4 |
| 58 |
27555891 | Pharmacogenetic studies update in type 2 diabetes mellitus. | 2016 Aug 10 |
1 |
| 59 |
25199921 | Proton pump inhibitors do not impair the effectiveness of metformin in patients with diabetes. | 2015 Feb |
1 |
| 60 |
25359200 | Organic cation transporter-mediated drug-drug interaction potential between berberine and metformin. | 2015 |
2 |
| 61 |
25492374 | Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patients. | 2015 Nov |
4 |
| 62 |
25510240 | Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study. | 2015 May |
6 |
| 63 |
25753371 | Multidrug and toxin extrusion 1 and human organic cation transporter 1 polymorphisms in patients with castration-resistant prostate cancer receiving metformin (SAKK 08/09). | 2015 Jun |
4 |
| 64 |
25939711 | Steady-state pharmacokinetics of metformin is independent of the OCT1 genotype in healthy volunteers. | 2015 Jun |
2 |
| 65 |
26335661 | Prediction and validation of enzyme and transporter off-targets for metformin. | 2015 Oct |
2 |
| 66 |
26426900 | Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein. | 2015 |
1 |
| 67 |
26464716 | Genetic variants of OCT1 influence glycemic response to metformin in Han Chinese patients with type-2 diabetes mellitus in Shanghai. | 2015 |
4 |
| 68 |
26526073 | Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug-drug interactions. | 2015 Dec |
1 |
| 69 |
26528626 | Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3). | 2015 Dec 7 |
2 |
| 70 |
25060604 | Verapamil decreases the glucose-lowering effect of metformin in healthy volunteers. | 2014 Dec |
4 |
| 71 |
25106415 | Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. | 2014 Nov |
1 |
| 72 |
22861817 | Differential expression of organic cation transporter OCT-3 in oral premalignant and malignant lesions: potential implications in the antineoplastic effects of metformin. | 2013 Mar |
2 |
| 73 |
22882994 | Pharmacogenomic association between a variant in SLC47A1 gene and therapeutic response to metformin in type 2 diabetes. | 2013 Feb |
1 |
| 74 |
23417334 | Influences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects. | 2013 Apr |
1 |
| 75 |
23873119 | A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin. | 2013 Oct |
1 |
| 76 |
23922447 | Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene. | 2013 Oct |
1 |
| 77 |
23984399 | Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology. | 2013 |
3 |
| 78 |
24145224 | Genetic polymorphisms potentially associated with response to metformin in postmenopausal diabetics suffering and not suffering with cancer. | 2013 Dec 1 |
1 |
| 79 |
24324494 | Pharmacogenetics of oral antidiabetic drugs. | 2013 |
1 |
| 80 |
24399729 | Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4α upregulation in primary human hepatocytes. | 2013 |
3 |
| 81 |
22038047 | Caveolin-1 is essential for metformin inhibitory effect on IGF1 action in non-small-cell lung cancer cells. | 2012 Feb |
2 |
| 82 |
22394605 | Inhibition of hepatic uptake transporters by flavonoids. | 2012 May 12 |
2 |
| 83 |
22415520 | Genetic variants of organic cation transporter 1 (OCT1) and OCT2 significantly reduce lamivudine uptake. | 2012 Apr |
2 |
| 84 |
22735389 | Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients. | 2012 Sep |
5 |
| 85 |
20567254 | Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions. | 2011 Dec |
6 |
| 86 |
20680652 | OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users. | 2011 Feb |
2 |
| 87 |
20956498 | OCT1 Expression in adipocytes could contribute to increased metformin action in obese subjects. | 2011 Jan |
2 |
| 88 |
21241070 | Clinical pharmacokinetics of metformin. | 2011 Feb |
1 |
| 89 |
21575951 | Responsiveness to metformin in girls with androgen excess: collective influence of genetic polymorphisms. | 2011 Jul |
1 |
| 90 |
21677353 | [Metformin - mechanisms of action and use for the treatment of type 2 diabetes mellitus]. | 2011 May 6 |
3 |
| 91 |
21779389 | Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs). | 2011 |
2 |
| 92 |
21986525 | Relevance of the OCT1 transporter to the antineoplastic effect of biguanides. | 2011 Nov 4 |
3 |
| 93 |
21989078 | The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c. | 2011 Dec |
6 |
| 94 |
22345987 | Genetic analysis of OCT1 gene polymorphisms in an Indian population. | 2011 Sep |
2 |
| 95 |
19898263 | Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response. | 2010 Jan |
6 |
| 96 |
20406215 | SLCO1B1 polymorphism and oral antidiabetic drugs. | 2010 Oct |
1 |
| 97 |
20639304 | Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function. | 2010 Oct |
6 |
| 98 |
20660041 | Organic cation transporter 1 polymorphisms predict the metabolic response to metformin in women with the polycystic ovary syndrome. | 2010 Oct |
6 |
| 99 |
20863201 | Sitagliptin attenuates metformin-mediated AMPK phosphorylation through inhibition of organic cation transporters. | 2010 Dec |
1 |
| 100 |
19002567 | Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis. | 2009 Mar |
1 |