Oximes

acetylcholinesterase ; Cavia porcellus







20 Article(s)
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1 33548273 The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs. 2021 Mar 15 2
2 31954867 Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy. 2020 May 15 1
3 29129798 The efficacy of HI-6 DMS in a sustained infusion against percutaneous VX poisoning in the guinea-pig. 2018 Sep 1 3
4 20971170 Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase. 2011 Jan 15 1
5 21989207 Oxidative mechanisms for the biotransformation of 1-methyl-1,6-dihydropyridine-2-carbaldoxime to pralidoxime chloride. 2011 Dec 19 1
6 19680820 Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication. 2010 Jan 5
7 20096273 Mechanism for potent reactivation ability of H oximes analyzed by reactivation kinetic studies with cholinesterases from different species. 2010 Sep 6 2
8 20156430 Pro-2-PAM therapy for central and peripheral cholinesterases. 2010 Sep 6 1
9 20433814 Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation. 2010 Sep 6 2
10 19428926 Comparison of the oxime-induced reactivation of rhesus monkey, swine and guinea pig erythrocyte acetylcholinesterase following inhibition by sarin or paraoxon, using a perfusion model for the real-time determination of membrane-bound acetylcholinesterase activity. 2009 Apr 28 3
11 19778238 In vivo oxime administration does not influence Ellman acetylcholinesterase assay results. 2009 Sep 6
12 19778239 Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose. 2009 Sep 2
13 18508103 A structure-activity analysis of the variation in oxime efficacy against nerve agents. 2008 Sep 1 2
14 12915103 Toxicokinetics of the nerve agent (+/-)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration. 2003 Aug 15 1
15 12242610 Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates. 2002 Sep 2
16 7576830 Effect of pyridostigmine pretreatment on cardiorespiratory function in tabun poisoning. 1995 Aug 1
17 7654137 Cardiorespiratory function in nerve agent poisoned and oxime + atropine treated guinea-pigs: effect of pyridostigmine pretreatment. 1995 1
18 2046471 Evaluation of phosphinates as potential pretreatments for nerve agents. 1991 3
19 3807651 Oxime-induced decarbamylation and atropine/oxime therapy of guinea pigs intoxicated with pyridostigmine. 1987 Feb 9 4
20 6262099 Analysis of oxime-induced neuromuscular recovery in guinea pig, rat and man following soman poisoning in vitro. 1981 Mar 26 1