Pub. Date : 2010 Jan
PMID : 19680820
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The capability of the tertiary oximes, monoisonitrosoacetone (MINA) and diacetylmonoxime (DAM), to reactivate acetylcholinesterase (AChE) inhibited by sarin (GB) in the blood, brain, and peripheral tissues of guinea pigs was compared with that of the quaternary oximes 2-PAM, HLo7, and MMB-4. | Oximes | acetylcholinesterase | Cavia porcellus |
2 | The capability of the tertiary oximes, monoisonitrosoacetone (MINA) and diacetylmonoxime (DAM), to reactivate acetylcholinesterase (AChE) inhibited by sarin (GB) in the blood, brain, and peripheral tissues of guinea pigs was compared with that of the quaternary oximes 2-PAM, HLo7, and MMB-4. | Oximes | acetylcholinesterase | Cavia porcellus |
3 | The capability of the tertiary oximes, monoisonitrosoacetone (MINA) and diacetylmonoxime (DAM), to reactivate acetylcholinesterase (AChE) inhibited by sarin (GB) in the blood, brain, and peripheral tissues of guinea pigs was compared with that of the quaternary oximes 2-PAM, HLo7, and MMB-4. | Oximes | acetylcholinesterase | Cavia porcellus |
4 | The capability of the tertiary oximes, monoisonitrosoacetone (MINA) and diacetylmonoxime (DAM), to reactivate acetylcholinesterase (AChE) inhibited by sarin (GB) in the blood, brain, and peripheral tissues of guinea pigs was compared with that of the quaternary oximes 2-PAM, HLo7, and MMB-4. | Oximes | acetylcholinesterase | Cavia porcellus |
5 | Thus, tertiary oximes reactivated AChE in the brain, improved survival, and terminated seizures following GB intoxication. | Oximes | acetylcholinesterase | Cavia porcellus |