| 1 |
35507892 | Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells. | 2022 May 3 |
1 |
| 2 |
30282838 | Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells. | 2019 Mar 1 |
2 |
| 3 |
31495784 | Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions. | 2019 Oct 25 |
1 |
| 4 |
29533741 | Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity. | 2018 Sep 1 |
2 |
| 5 |
30354239 | Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow. | 2018 Nov |
2 |
| 6 |
27678191 | miR-467b regulates the cholesterol ester formation via targeting ACAT1 gene in RAW 264.7 macrophages. | 2017 Jan |
1 |
| 7 |
26801614 | Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression. | 2016 Mar 18 |
3 |
| 8 |
26017812 | Oxidized-low density lipoprotein accumulates cholesterol esters via the PKCα-adipophilin-ACAT1 pathway in RAW264.7 cells. | 2015 Sep |
3 |
| 9 |
26669800 | ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease. | 2015 |
1 |
| 10 |
24657401 | Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells. | 2014 Jul |
1 |
| 11 |
25264044 | Role of ACAT1-positive late endosomes in macrophages: cholesterol metabolism and therapeutic applications for Niemann-Pick disease type C. | 2014 |
1 |
| 12 |
25339759 | Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance. | 2014 Oct 22 |
2 |
| 13 |
25522268 | TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression. | 2014 Dec 18 |
1 |
| 14 |
23395977 | Cholesterol loading affects osteoblastic differentiation in mouse mesenchymal stem cells. | 2013 Apr |
1 |
| 15 |
23601809 | Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice. | 2013 Sep |
1 |
| 16 |
23774792 | Acat1 knockdown gene therapy decreases amyloid-β in a mouse model of Alzheimer's disease. | 2013 Aug |
2 |
| 17 |
22427949 | Perilipin 2 (PLIN2)-deficiency does not increase cholesterol-induced toxicity in macrophages. | 2012 |
1 |
| 18 |
23123480 | 2,3,22,23-tetrahydroxyl-2,6,10,15,19,23-hexamethyl-6,10,14,18-tetracosatetraene, an acyclic triterpenoid isolated from the seeds of Alpinia katsumadai, Inhibits acyl-CoA : cholesterol acyltransferase activity. | 2012 |
1 |
| 19 |
19866465 | Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model. | 2010 Mar 1 |
1 |
| 20 |
20133765 | ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. | 2010 Feb 16 |
1 |
| 21 |
18618086 | Novel N-terminal cleavage of APP precludes Abeta generation in ACAT-defective AC29 cells. | 2009 Jan |
1 |
| 22 |
19652367 | The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophages. | 2009 Aug |
1 |
| 23 |
18502767 | Microsomal triglyceride transfer protein enhances cellular cholesteryl esterification by relieving product inhibition. | 2008 Jul 18 |
1 |
| 24 |
16144700 | ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages. | 2006 Jun |
1 |
| 25 |
15499044 | ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages. | 2005 Jan |
1 |
| 26 |
15831806 | ACAT2 is a target for treatment of coronary heart disease associated with hypercholesterolemia. | 2005 Jun |
1 |
| 27 |
14617738 | Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay: individual ACAT uniqueness. | 2004 Feb |
2 |
| 28 |
12518025 | ACBP and cholesterol differentially alter fatty acyl CoA utilization by microsomal ACAT. | 2003 Jan |
1 |
| 29 |
14704742 | Macrophages, inflammation, and atherosclerosis. | 2003 Dec |
1 |
| 30 |
12200416 | Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin. | 2002 Nov 8 |
1 |
| 31 |
11160132 | Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. | 2001 Jan |
1 |
| 32 |
11264983 | Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. | 2001 Apr |
2 |
| 33 |
11100106 | Cholesterol esters and atherosclerosis-a game of ACAT and mouse. | 2000 Dec |
1 |
| 34 |
9559268 | Acyl CoA:cholesterol acyltransferase genes and knockout mice. | 1998 Apr |
1 |
| 35 |
9684737 | Lysosomal sequestration of free and esterified cholesterol from oxidized low density lipoprotein in macrophages of different species. | 1998 Jul |
1 |
| 36 |
2393386 | Oxidized LDL increase free cholesterol and fail to stimulate cholesterol esterification in murine macrophages. | 1990 Aug 31 |
1 |
| 37 |
3624250 | Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein. | 1987 Sep 5 |
1 |
| 38 |
3949765 | Inhibition of acyl coenzyme A:cholesterol acyl transferase in J774 macrophages enhances down-regulation of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase and prevents low density lipoprotein-induced cholesterol accumulation. | 1986 Mar 5 |
1 |
| 39 |
20482 | Effect of dietary fat saturation on acylcoenzyme A:-cholesterol acyltransferase activity of Ehrlich cell microsomes. | 1977 Sep |
1 |