Pub. Date : 2016 Mar 18
PMID : 26801614
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Acyl-CoA:cholesterol acyltransferase 1 (Acat1) converts cellular cholesterol to cholesteryl esters and is considered a drug target for treating atherosclerosis. | Cholesterol Esters | acetyl-Coenzyme A acetyltransferase 1 | Mus musculus |
| 2 | Acyl-CoA:cholesterol acyltransferase 1 (Acat1) converts cellular cholesterol to cholesteryl esters and is considered a drug target for treating atherosclerosis. | Cholesterol Esters | acetyl-Coenzyme A acetyltransferase 1 | Mus musculus |
| 3 | Analyses of atherosclerotic lesions showed that Acat1(-M/-M) reduced macrophage numbers and diminished the cholesterol and cholesteryl ester load without causing detectable apoptotic cell death. | Cholesterol Esters | acetyl-Coenzyme A acetyltransferase 1 | Mus musculus |