Title : Protein synthesis inhibition in mouse peritoneal macrophages results in increased acyl coenzyme A:cholesterol acyl transferase activity and cholesteryl ester accumulation in the presence of native low density lipoprotein.

Pub. Date : 1987 Sep 5

PMID : 3624250






1 Functional Relationships(s)
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Protein Name
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1 Cholesteryl ester (CE) accumulation in arterial wall macrophages (foam cells), mediated by the intracellular enzyme acyl coenzyme A:cholesterol acyl transferase (ACAT), is a prominent feature of atherosclerotic lesions. Cholesterol Esters acetyl-Coenzyme A acetyltransferase 1 Mus musculus