5-hydroxymethylcytosine

isocitrate dehydrogenase (NADP(+)) 1 ; Homo sapiens







15 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35501312 Rare and misincorporated DNA N6-methyladenine is a hallmark of cytotoxic stresses for selectively stimulating the stemness and proliferation of glioblastoma cells. 2022 Apr 30 1
2 30724377 Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues. 2019 May 4
3 29428975 5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma. 2018 Apr 2
4 28039446 5-Hydroxymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia. 2017 Jan 31 2
5 26680004 Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer. 2016 Jan 1
6 27458708 Immunohistochemical loss of 5-hydroxymethylcytosine expression in acute myeloid leukaemia: relationship to somatic gene mutations affecting epigenetic pathways. 2016 Dec 3
7 27466503 Isocitrate Dehydrogenase 2 Dysfunction Contributes to 5-hydroxymethylcytosine Depletion in Gastric Cancer Cells. 2016 Aug 1
8 24986689 Characterization of acute myeloid leukemia based on levels of global hydroxymethylation. 2014 Aug 14 1
9 25482556 DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. 2014 Dec 11 2
10 22824796 Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. 2013 Jun 20 1
11 23634848 5-hydroxymethylcytosine and its potential roles in development and cancer. 2013 May 1 2
12 22688054 Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas. 2012 Aug 1
13 22772731 IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase activities in astroglioma. 2012 Sep 1
14 21251613 Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. 2011 Jan 18 2
15 21690245 TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations. 2011 Oct 1