Title : DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.

Pub. Date : 2014 Dec 11

PMID : 25482556






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Somatic mutations in IDH1/IDH2 and TET2 result in impaired TET2-mediated conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). 5-hydroxymethylcytosine isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens
2 Somatic mutations in IDH1/IDH2 and TET2 result in impaired TET2-mediated conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). 5-hydroxymethylcytosine isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens