Title : 5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma.

Pub. Date : 2018 Apr

PMID : 29428975






2 Functional Relationships(s)
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1 To characterize 5hmC in IDH1 mutant gliomas further, we examine 5hmC in a cohort of IDH1 mutant and wild-type high-grade gliomas (HGG) using a quantitative locus-specific approach. 5-hydroxymethylcytosine isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens
2 Among these regions, IDH1 mutant tumors possess greater 5hmC compared to wild type. 5-hydroxymethylcytosine isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens