Pub. Date : 2013 May 1
PMID : 23634848
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Since TET proteins and many lysine demethylases require 2-oxoglutarate as a cofactor, aberrations in cofactor biochemical pathways, including mutations in isocitrate dehydrogenase (IDH), may affect levels of 5hmC and 5mC in certain types of tumors, either directly or indirectly. | 5-hydroxymethylcytosine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |
| 2 | Since TET proteins and many lysine demethylases require 2-oxoglutarate as a cofactor, aberrations in cofactor biochemical pathways, including mutations in isocitrate dehydrogenase (IDH), may affect levels of 5hmC and 5mC in certain types of tumors, either directly or indirectly. | 5-hydroxymethylcytosine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |